2-methylthio-ATP

We have cloned and expressed a novel human G-protein-coupled receptor closely related to the human P2Y(12) receptor. It… (More)

Rationale: Previous experiments have shown that P2 receptor activation increases the release of dopamine in the mesolimbic… (More)

The antagonist activity of N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate (N6MABP) has been examined at the phospholipase C… (More)

An intronless open reading frame encoding a protein (361aa in length) was isolated from a rat genomic library probed with a DNA… (More)

1. Under voltage-clamp conditions, the activity of agonists and antagonists at a recombinant P2X2 receptor expressed in Xenopus… (More)

1. Whole-cell and single-channel K+ currents were recorded at room temperature (22-24 degrees C), from smooth muscle cells… (More)

1. The coding sequence of the P2Y1-purinoceptor was cloned from a human genomic library. 2. The open reading frame encodes a… (More)

1. Whole-cell recordings were made from guinea-pig coeliac, rat nodose and rat superior cervical (SCG) neurones in culture, and… (More)

1 The role of extracellular nucleotides in regulation of ion transport activities (short circuit current, Isc) of human… (More)

The term purinergic receptor (or purinoceptor) was first introduced to describe classes of membrane receptors that, when… (More)