Skip to search formSkip to main contentSkip to account menu

2-guanidine-4-methylquinazoline

Known as: 2-GMQ 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

GuanidinesQuinazolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Functional involvement of acid‐sensing ion channel 3 in the swallowing reflex in rats
Difficulty swallowing represents a major health problem. Swallowing function is improved by incorporating weak acids in… 
2018
2018
Expression of ASIC3 in the Trigeminal Nucleus Caudalis Plays a Role in a Rat Model of Recurrent Migraine
Acid-sensing ion channel 3 (ASIC3) is abundant in the trigeminal nervous system and is most sensitive to a slight pH decrease… 
2018
2018
Multiple regulatory actions of 2‐guanidine‐4‐methylquinazoline (GMQ), an agonist of acid‐sensing ion channel type 3, on ionic currents in pituitary GH3 cells and in olfactory sensory (Rolf B1.T…
2017
2017
Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers
Acid-sensing ion channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extracellular… 
2017
2017
The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of the native FMRFamide peptide
The degenerin/epithelial sodium channel (DEG/ENaC) superfamily of ion channels contains subfamilies with diverse functions that… 
2014
2014
Protons and Psalmotoxin-1 reveal nonproton ligand stimulatory sites in chicken acid-sensing ion channel
Acid-sensing ion channels (ASICs) are proton-sensitive, sodium-selective channels expressed in the nervous system that sense… 
2013
2013
2-Guanidine-4-methylquinazoline acts as a novel competitive antagonist of A type γ-aminobutyric acid receptors
Highly Cited
2012
Highly Cited
2012
Subtype-specific Modulation of Acid-sensing Ion Channel (ASIC) Function by 2-Guanidine-4-methylquinazoline*
Background: The small molecule GMQ opens ASIC3 channels by an unknown mechanism. Results: GMQ alters pH-dependent gating in all… 
Highly Cited
2010
Highly Cited
2010
ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain
BackgroundAcid-sensing ion channels (ASICs) have long been known to sense extracellular protons and contribute to sensory… 
1996
1996
Effects of 2-guanidine-4-methylquinazoline on gastric acid secretion in rats.
In this study 2-guanidine-4-methylquinazoline (2-GMQ) appeared to decrease basal and stimulated gastric acid secretion, while… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)