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2-ethynylnaphthalene

National Institutes of Health

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Naphthalenes

Papers overview

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2018
2018
Self-Reaction of ortho-Benzyne at High Temperatures Investigated by Infrared and Photoelectron Spectroscopy.
ortho-Benzyne, a Kekulé-type biradical is considered to be a key intermediate in the formation of polycyclic aromatic… 
2018
2018
The influence of conjugated alkynyl(aryl) surface groups on the optical properties of silicon nanocrystals: photoluminescence through in-gap states
Developing new methods, other than size and shape, for controlling the optoelectronic properties of semiconductor nanocrystals is… 
2007
2007
Inhibition of CYP2B4 by the mechanism-based inhibitor 2-ethynylnaphthalene: inhibitory potential of 2EN is dependent on the size of the substrate.
2007
2007
Inhibition of CYP2B4 by 2-ethynylnaphthalene: evidence for the co-binding of substrate and inhibitor within the active site.
2003
2003
Threonine-205 in the F Helix of P450 2B1 Contributes to Androgen 16β-Hydroxylation Activity and Mechanism-Based Inactivation
Four mutants of Thr-205 in cytochrome P450 2B1 were constructed and expressed in Escherichia coli. The Ser-, Ala-, and Val… 
1997
1997
INACTIVATION OF CYTOCHROME P 450 S 2 B 1 , 2 B 4 , 2 B 6 , AND 2 B 11 BY ARYLALKYNES
The time-dependent loss of the 7-ethoxy-4-trifluoromethylcoumarin (EFC) O-deethylase activity of rat P450 2B1, rabbit P450 2B4… 
1993
1993
Cytochrome P4501A1 mediates the metabolism of 2,3,7,8-tetrachlorodibenzofuran in the rat and human.
Previous studies have established that TCDF is rapidly metabolized and excreted in rats and that pretreatment of rats with TCDD… 
1993
1993
Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone mouse lung tumorigenesis by arylalkynes, mechanism-based inactivators of cytochrome P450.
Arylalkynes such as 4-phenyl-1-butyne (PBY), 5-phenyl-1-pentyne (PPY) and 2-ethynylnaphthalene (2-EN) are suicide inhibitors of… 
1989
1989
2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine.
Since the N-oxidation of several carcinogenic arylamines has been shown to be catalyzed preferentially by cytochrome P-450IA2 in… 
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