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2-bromopalmitate

Known as: 2-bromohexadecanoic acid, alpha-bromopalmitate 
 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
2-Bromohexadecanoic acid, or 2-bromopalmitate, was introduced nearly 50 years ago as a nonselective inhibitor of lipid metabolism… Expand
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2013
2013
S-acylation, the covalent attachment of palmitate and other fatty acids on cysteine residues, is a reversible post-translational… Expand
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Highly Cited
2007
Highly Cited
2007
Elevated levels of free fatty acids contribute to cardiovascular diseases, but the mechanisms remain poorly understood. The… Expand
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Highly Cited
2004
Highly Cited
2004
Wnt signaling pathways regulate many developmental responses; however, little is known about how Wnt ligands function on a… Expand
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Highly Cited
2000
Highly Cited
2000
The ability of the Src family kinases Fyn and Lck to participate in signaling through the T cell receptor is critically dependent… Expand
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Highly Cited
2000
Highly Cited
2000
Free fatty acid (FFA) has been reported to decrease leptin mRNA levels in 3T3-L1 adipocytes. When using this cell line, it is… Expand
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Highly Cited
1994
Highly Cited
1994
Fatty acids are important metabolic substrates for adipose tissue and act, in preadipose cells, as potent inducers of various… Expand
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Highly Cited
1994
Highly Cited
1994
We sought to explore the emerging concept that malonyl-CoA generation, with concomitant suppression of mitochondrial carnitine… Expand
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Highly Cited
1992
Highly Cited
1992
2-Bromopalmitate and 2-bromopalmitoyl-CoA have been shown to inhibit a variety of enzymes and proteins associated with lipid… Expand
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Highly Cited
1972
Highly Cited
1972
1. The CoA and carnitine esters of 2-bromopalmitate are extremely powerful and specific inhibitors of mitochondrial fatty acid… Expand
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