2-Naphthylamine

Known as: beta Naphthylamine, 2 Aminonaphthalene, 2-Naphthylamine [Chemical/Ingredient] 
A synthetic, air-sensitive, colorless crystalline solid that is soluble in hot water, alcohol, ether and many organic solvents. Currently, it is only… (More)
National Institutes of Health

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1,5-diaminonaphthalene1,8-diaminonaphthalene2,3-diamino-1,4-dibromonaphthalene2,3-diaminonaphthalene
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Carcinogens
analogs & derivativesaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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1998
1998
Protection from oxidative inactivation of the 20S proteasome by heat-shock protein 90.
Heat-shock protein 90 (Hsp 90) has been implicated in both protection against oxidative inactivation and inhibition of the… (More)
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Highly Cited
1996
Highly Cited
1996
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
A human cytochrome P-450 (P450) 1B1 cDNA was expressed in Saccharomyces cerevisiae and the microsomes containing P450 1B1 were… (More)
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Highly Cited
1993
Highly Cited
1993
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
A genetic polymorphism at the NAT2 gene locus, encoding for polymorphic N-acetyltransferase (NAT2), segregates individuals into… (More)
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Highly Cited
1989
Highly Cited
1989
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
Aromatic amines are well known as occupational carcinogens and are found in cooked foods, tobacco smoke, synthetic fuels, and… (More)
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1983
1983
Generation of hydrogen peroxide and superoxide anion from active metabolites of naphthylamines and aminoazo dyes: its possible role in carcinogenesis.
Autoxidation of active metabolites of naphthylamine and aminoazo dyes in neutral buffer generated hydrogen peroxide (H2O2) and… (More)
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Highly Cited
1980
Highly Cited
1980
Screening of tobacco smoke constituents for mutagenicity using the Ames' test.
To clarify the mutagenic activity of individual smoke components, 239 compounds, representative of the gaseous and semivolatile… (More)
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1977
1977
Degradation of myofibrillar proteins by cathepsins B and D.
Cathepsin B and cathepsin D were purified from rat liver and skeletal muscle. Electrophoretic analyses revealed that the enzymes… (More)
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1963
1963
Carcinogenicity of 2-Naphthylhydroxylamine and 2-Naphthylamine
THE discovery of the N-hydroxylation of 2-acetamidofluorene in vivo (Cramer, Miller and Miller, 1959) had been followed by… (More)
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1956
1956
The Carcinogenic Activity of 2-Naphthylamine
HUEPER (1938) and Bonser (1943) established that carcinoma of the bladder may be induced by feeding 2-naphthylamine to dogs over… (More)
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1952
1952
The Carcinogenic Properties of 2-Amino-1-Naphthol Hydrochloride and its Parent Amine 2-Naphthylamine
IN 1951, Bonser, Clayson and Jull published some of the results of a quantitative study of the metabolism of 2-naphthylamine by… (More)
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