2,5-hexanedione

Known as: diacetonyl, 2,5-diketohexane, hexanedione, 2,5- 
 
National Institutes of Health

Papers overview

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2011
2011
Studies have shown that 2,5-hexanedione (2,5-HD) is the main active metabolite of n-hexane in the human body. The toxicity of n… (More)
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2007
2007
Sertoli cells are the primary cellular target for a number of pharmaceutical and environmental testicular toxicants, including 2… (More)
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2004
2004
2,5-Hexanedione (2,5-HD), a taxol-like promoter of microtubule assembly, and carbendazim (CBZ), a colchicine-like inhibitor of… (More)
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2004
2004
A number of C(4)-C9 aliphatic ketones, including 2,5-hexanedione (2,5-HD), are acetylcholinesterase (AChE; EC 3.1.1.7) inhibitors… (More)
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2002
2002
This research was conducted to determine which neurological test or combination of tests can provide sufficient functional… (More)
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Highly Cited
1997
Highly Cited
1997
Apoptosis occurs in the testis as an important physiological mechanism to limit the number of germ cells in the seminiferous… (More)
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1996
1996
2,5-hexanedione (2,5-HD) is a Sertoli cell toxicant which causes germ cell loss and testicular atrophy in the rat. The mechanism… (More)
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1985
1985
Chronic oral administration of a combination of 2.2 mmol methyl ethyl ketone (MEK) and 2.2 mmol 2,5-hexanedione (2,5-HD)/kg/day… (More)
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Review
1982
Review
1982
Human exposure to hexacarbon compounds is quite pervasive, including occupational exposures to industrial solvents as well as… (More)
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1978
1978
Distinctive cytoplasmic alterations of Schwann cells were observed by electron microscopy in rats and mice with peripheral… (More)
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