2,4-diaminohypoxanthine

Known as: 2,4-DAHP, 2,4-diamino-6-hydroxypyrimidine, DHAP-2,4 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2015
024619762015

Papers overview

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2010
2010
Gastroparesis is a debilitating disease predominantly affecting young women. Recently, dysregulation of neuronal nitric oxide… (More)
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2008
2008
GTP cyclohydrolase 1 (GTPCH1) is the rate-limiting enzyme in de novo synthesis of tetrahydrobiopterin (BH4), an essential… (More)
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Highly Cited
2007
Highly Cited
2007
An essential cofactor for the endothelial NO synthase is tetrahydrobiopterin (H4B). In the present study, we show that in human… (More)
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2003
2003
OBJECTIVE Endothelial nitric oxide synthase (eNOS) activity is supported by tetrahydrobiopterin (BH4), which appears to be… (More)
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2003
2003
The mechanisms leading to microangiopathy in diabetes mellitus have still not been clearly elucidated. We hypothesized that type… (More)
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Highly Cited
2002
Highly Cited
2002
1. Endothelium-dependent and -independent regulation of vascular tone in small mesenteric arteries (SMA) from control (db/db… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Free radicals such as superoxide and nitric oxide (NO) play a key role in the pathophysiology of atherosclerosis… (More)
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1996
1996
BACKGROUND A deficit in the endothelial production of nitric oxide (NO) is associated with the sequelae of reperfusion injury… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND The L-arginine/nitric oxide pathway plays a key role in the regulation of arterial tone. Biosynthesis of nitric oxide… (More)
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1993
1993
The murine macrophage cell line RAW 264 constitutively synthesizes tetrahydrobiopterin (BH4), the cofactor required for the… (More)
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