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2,2'-dipyridyl disulfide

Known as: 2,2-dithiobispyridine, 2,2'-dithiodipyridine, 2,2-PDS 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

2,2'-DipyridylDisulfidesOxidants

Narrower (1)

Aldrithiol-2
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
O2 Modulates Large-Conductance Ca2+-Dependent K+ Channels of Rat Chemoreceptor Cells by a Membrane-Restricted and CO-Sensitive Mechanism
Hypoxic inhibition of large-conductance Ca2+-dependent K+ channels (maxiK) of rat carotid body type I cells is a well-established… Expand
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Highly Cited
2001
Highly Cited
2001
p38 Activation Is Required Upstream of Potassium Current Enhancement and Caspase Cleavage in Thiol Oxidant-Induced Neuronal Apoptosis
Oxidant-induced neuronal apoptosis has been shown to involve potassium and zinc dysregulation, energetic dysfunction, activation… Expand
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Highly Cited
2000
Highly Cited
2000
Induction of Neuronal Apoptosis by Thiol Oxidation
Abstract: The membrane‐permeant oxidizing agent 2,2′‐dithiodipyridine (DTDP) can induce Zn2+ release from metalloproteins in cell… Expand
Highly Cited
1998
Highly Cited
1998
Sulfhydryl oxidation modifies the calcium dependence of ryanodine-sensitive calcium channels of excitable cells.
The calcium dependence of ryanodine-sensitive single calcium channels was studied after fusing with planar lipid bilayers… Expand
Highly Cited
1998
Highly Cited
1998
Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine.
Although most viral vaccines used in humans have been composed of live attenuated viruses or whole killed viral particles, the… Expand
Highly Cited
1997
Highly Cited
1997
Redox Regulation of Large Conductance Ca2+-activated K+ Channels in Smooth Muscle Cells
The effects of sulfhydryl reduction/oxidation on the gating of large-conductance, Ca2+-activated K+ (maxi-K) channels were… Expand
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Highly Cited
1995
Highly Cited
1995
Functional consequences of sulfhydryl modification in the pore-forming subunits of cardiovascular Ca2+ and Na+ channels.
The structure and function of many cysteine-containing proteins critically depend on the oxidation state of the sulfhydryl groups… Expand
Highly Cited
1994
Highly Cited
1994
A procedure for quantitative determination of tris(2-carboxyethyl)phosphine, an odorless reducing agent more stable and effective than dithiothreitol.
  • J. Han, G. Han
  • Analytical biochemistry
  • 1994
    • Corpus ID: 27991954
The concentration of tris(2-carboxyethyl)phosphine (TCEP) can be conveniently determined by measuring the amount of 2-nitro-5… Expand
Highly Cited
1981
Highly Cited
1981
Electrostatic influence of local cysteine environments on disulfide exchange kinetics.
The ionic strength dependence of the bimolecular rate constant for reaction of the negative disulfide 5,5'-dithiobis (2… Expand
Highly Cited
1980
Highly Cited
1980
Reactivity of the thiol group in human and bovine albumin at pH 3--9, as measured by exchange with 2,2'-dithiodipyridine.
The kinetics for exchange between an aromatic disulphide and the thiol group in human and bovine albumin as well as in… Expand
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