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2',3'-dideoxythymidine triphosphate
Known as:
ddTTP
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Dideoxynucleotides
Thymine Nucleotides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Differential Incorporation and Removal of Antiviral Deoxynucleotides by Human DNA Polymerase γ*
Susan E. Lim
,
W. Copeland
Journal of Biological Chemistry
2001
Corpus ID: 34515938
Mitochondrial toxicity can result from antiviral nucleotide analog therapy used to control human immunodeficiency virus type 1…
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Highly Cited
2001
Highly Cited
2001
Crystal structures of a ddATP‐, ddTTP‐, ddCTP, and ddGTP‐ trapped ternary complex of Klentaq1: Insights into nucleotide incorporation and selectivity
Y. Li
,
G. Waksman
Protein Science
2001
Corpus ID: 6209850
The mechanism by which DNA polymerase I enzymes function has been the subject of extensive biochemical and structural studies. We…
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Highly Cited
1999
Highly Cited
1999
Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
C. Masutani
,
M. Araki
,
+5 authors
F. Hanaoka
EMBO Journal
1999
Corpus ID: 38795128
Xeroderma pigmentosum variant (XP‐V) represents one of the most common forms of this cancer‐prone DNA repair syndrome. Unlike…
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Highly Cited
1994
Highly Cited
1994
The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.
C. Strahl
,
E. Blackburn
Nucleic Acids Research
1994
Corpus ID: 15377394
The ribonucleoprotein enzyme telomerase is a specialized type of cellular reverse transcriptase which synthesizes one strand of…
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Highly Cited
1993
Highly Cited
1993
Identification of a nonprocessive telomerase activity from mouse cells.
K. Prowse
,
A. Avilion
,
C. Greider
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 27495537
Telomerase activity was identified in extracts from several different mouse cell lines. Addition of telomeric TTAGGG repeats was…
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Highly Cited
1990
Highly Cited
1990
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
J. Holmes
,
S. Clark
,
P. Modrich
Proceedings of the National Academy of Sciences…
1990
Corpus ID: 25813706
Nuclear extracts derived from HeLa and Drosophila melanogaster KC cell lines have been found to correct single base-base mispairs…
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Highly Cited
1989
Highly Cited
1989
Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.
J. Shoffner
,
M. Lott
,
A. Voljavec
,
S. Soueidan
,
D. Costigan
,
D. Wallace
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 44639959
The muscle mitochondria of a patient with Kearns-Sayre/chronic external ophthalmoplegia plus syndrome were found to be completely…
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Highly Cited
1981
Highly Cited
1981
Formation of a covalent complex between the 80,000-dalton adenovirus terminal protein and 5'-dCMP in vitro.
J. Lichy
,
M. Horwitz
,
J. Hurwitz
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 7484943
An in vitro adenovirus DNA replication system catalyzed the formation of a covalent complex between an 80,000-dalton protein and…
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Highly Cited
1980
Highly Cited
1980
Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells.
Y. Ishii
,
M. Bender
Mutation research
1980
Corpus ID: 38779296
Highly Cited
1978
Highly Cited
1978
Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication.
M. Waqar
,
M. J. Evans
,
J. Huberman
Nucleic Acids Research
1978
Corpus ID: 20506435
We have studied the effects of the nucleotide analogue, 2',3'-dideoxythymidine-5'-triphosphate (ddTTP) on replicative DNA…
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