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2',3'-dideoxythymidine triphosphate

Known as: ddTTP 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

DideoxynucleotidesThymine Nucleotides

Papers overview

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Highly Cited
2001
Highly Cited
2001
Differential Incorporation and Removal of Antiviral Deoxynucleotides by Human DNA Polymerase γ*
Mitochondrial toxicity can result from antiviral nucleotide analog therapy used to control human immunodeficiency virus type 1… Expand
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Highly Cited
2001
Highly Cited
2001
Crystal structures of a ddATP‐, ddTTP‐, ddCTP, and ddGTP‐ trapped ternary complex of Klentaq1: Insights into nucleotide incorporation and selectivity
  • Y. Li, G. Waksman
  • Protein science : a publication of the Protein…
  • 2001
    • Corpus ID: 6209850
The mechanism by which DNA polymerase I enzymes function has been the subject of extensive biochemical and structural studies. We… Expand
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Highly Cited
1999
Highly Cited
1999
Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity
Xeroderma pigmentosum variant (XP‐V) represents one of the most common forms of this cancer‐prone DNA repair syndrome. Unlike… Expand
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Highly Cited
1994
Highly Cited
1994
The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.
The ribonucleoprotein enzyme telomerase is a specialized type of cellular reverse transcriptase which synthesizes one strand of… Expand
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Highly Cited
1993
Highly Cited
1993
Identification of a nonprocessive telomerase activity from mouse cells.
Telomerase activity was identified in extracts from several different mouse cell lines. Addition of telomeric TTAGGG repeats was… Expand
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Highly Cited
1990
Highly Cited
1990
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
Nuclear extracts derived from HeLa and Drosophila melanogaster KC cell lines have been found to correct single base-base mispairs… Expand
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Highly Cited
1989
Highly Cited
1989
Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.
The muscle mitochondria of a patient with Kearns-Sayre/chronic external ophthalmoplegia plus syndrome were found to be completely… Expand
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Highly Cited
1982
Highly Cited
1982
The roles of DNA polymerases alpha, beta, and gamma in DNA repair synthesis induced in hamster and human cells by different DNA damaging agents.
The involvement of DNA polymerases alpha, beta, and gamma in DNA repair synthesis was investigated in subcellular preparations of… Expand
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Highly Cited
1981
Highly Cited
1981
Formation of a covalent complex between the 80,000-dalton adenovirus terminal protein and 5'-dCMP in vitro.
An in vitro adenovirus DNA replication system catalyzed the formation of a covalent complex between an 80,000-dalton protein and… Expand
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Highly Cited
1978
Highly Cited
1978
Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication.
We have studied the effects of the nucleotide analogue, 2',3'-dideoxythymidine-5'-triphosphate (ddTTP) on replicative DNA… Expand
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