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12-S-HETE

Known as: 12 S Hydroxyeicosatetraenoic Acid, 12-S-Hydroxyeicosatetraenoic Acid, Acid, 12-S-Hydroxyeicosatetraenoic 
National Institutes of Health

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Broader (1)

Hydroxyeicosatetraenoic Acids

Papers overview

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2020
2020
12(S)-HETE mediates diabetes induced endothelial dysfunction by activating intracellular endothelial cell TRPV1.
Diabetic patients develop endothelial dysfunction shortly after diabetes onset that progresses to vascular disease underlying the… 
2014
2014
Liquid chromatography-tandem mass spectrometry for simultaneous measurement of thromboxane B2 and 12(S)-hydroxyeicosatetraenoic acid in serum.
2007
2007
15(S)-HETE production in human retinal microvascular endothelial cells by hypoxia: Novel role for MEK1 in 15(S)-HETE induced angiogenesis.
PURPOSE To examine for the expression of 15-lipoxygenase 1 (15-LOX1) and 15-LOX2 in human retinal microvascular endothelial cells… 
2002
2002
12(S)-HETE, pleiotropic functions, multiple signaling pathways.
The arachidonic acid metabolite of 12 lipoxygenase, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) promotes metastatic behavior… 
Highly Cited
2002
Highly Cited
2002
The Oxidized Lipid and Lipoxygenase Product 12(S)-Hydroxyeicosatetraenoic Acid Induces Hypertrophy and Fibronectin Transcription in Vascular Smooth Muscle Cells via p38 MAPK and cAMP Response Element…
Evidence suggests that the arachidonic acid metabolite of 12-lipoxygenase, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE), not… 
2000
2000
Eicosanoid 12(S)-HETE activates phosphatidylinositol 3-kinase.
The arachidonic acid metabolite of 12 lipoxygenase, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) promotes metastatic behavior… 
Highly Cited
1997
Highly Cited
1997
Elevated 12-lipoxygenase activity in the spontaneously hypertensive rat.
Highly Cited
1994
Highly Cited
1994
Enhanced endothelial cell retraction mediated by 12(S)-HETE: a proposed mechanism for the role of platelets in tumor cell metastasis.
Platelets have been hypothesized to contribute to tumor cell metastasis, but the underlying mechanism(s) remain unknown. We… 
1990
1990
High-affinity binding and lack of growth-promoting activity of 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) in a human epidermal cell line.
The arachidonic acid metabolite 12-hydroxyeicosatetraenoic acid (12-HETE) is assumed to play an important role in skin physiology… 
Review
1989
Review
1989
Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)‐HETE‐induced endothelial cell retraction
A 12‐lipoxygenase metabolite of arachidonic acid, 12(S)‐hydroxyeicosatetraenoic acid (12[S]‐HETE), which is produced by platelets… 
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