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1,N(2)-propanodeoxyguanosine

 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Deoxyguanosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies.
Acrolein (Acr) is a ubiquitous environmental pollutant found in cigarette smoke and automobile exhaust. It can also be produced… Expand
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2011
2011
Analysis of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human leukocyte DNA from smokers and nonsmokers.
Cigarette smoking is a major source of human exposure to acrolein, a widespread environmental pollutant and toxicant that is also… Expand
2009
2009
Acrolein-derived DNA adduct formation in human colon cancer cells: its role in apoptosis induction by docosahexaenoic acid.
The apoptotic effects of docosahexaenoic acid (DHA) and other omega-3 polyunsaturated fatty acids (PUFAs) have been documented in… Expand
Highly Cited
2006
Highly Cited
2006
Analysis of crotonaldehyde- and acetaldehyde-derived 1,n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry.
Crotonaldehyde, a mutagen and carcinogen, reacts with deoxyguanosine (dGuo) in DNA to generate a pair of diastereomeric 1,N(2… Expand
2003
2003
1,N2-propanodeoxyguanosine adducts of the 1,3-butadiene metabolite, hydroxymethylvinyl ketone.
1,3-Butadiene (BD) is a rodent and human carcinogen. While several epoxides formed during BD metabolism are mutagenic and may… Expand
2002
2002
Structure of the 1,N(2)-propanodeoxyguanosine adduct in a three-base DNA hairpin loop derived from a palindrome in the Salmonella typhimurium hisD3052 gene.
The solution structure of the 1,N(2)-propanodeoxyguanosine (PdG) adduct was determined in a 3-base hairpin loop formed by d… Expand
2001
2001
Cancer risk assessment for the environmental mutagen and carcinogen crotonaldehyde on the basis of TD(50) and comparison with 1,N(2)-propanodeoxyguanosine adduct levels.
  • E. Eder, Budiawan
  • Cancer epidemiology, biomarkers & prevention : a…
  • 2001
    • Corpus ID: 113463
Humans are ubiquitously exposed to crotonaldehyde to a strongly varying extent, in particular, via food and alcoholic beverages… Expand
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2001
2001
1,N(2)-propanodeoxyguanosine adduct formation in aortic DNA following inhalation of acrolein.
Recent reports indicate that many of the cytotoxic and health-threatening components of environmental tobacco smoke (ETS) reside… Expand
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2000
2000
Development of a (32)P-postlabeling method for the detection of 1,N(2)-propanodeoxyguanosine adducts of trans-4-hydroxy-2-nonenal in vivo.
A (32)P-postlabeling method was developed for the sensitive detection of 1,N(2)-propanodeoxyguanosine adducts of the lipid… Expand
2000
2000
Detection of 1,N(2)-propanodeoxyguanosine adducts in DNA of Fischer 344 rats by an adapted (32)P-post-labeling technique after per os application of crotonaldehyde.
Crotonaldehyde is an important industrial chemical to which humans and animals are ubiquitously exposed. The main intake occurs… Expand
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