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1,4-diazepane

National Institutes of Health

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Azepines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Computational systematic selectivity of the Fasalog inhibitors between ROCK-I and ROCK-II kinase isoforms in Alzheimer's disease
2019
2019
Synthesis, Cytotoxicity Evaluation, and Computational Insights of Novel 1,4-Diazepane-Based Sigma Ligands.
Among several potential applications, sigma receptor ligands can be used as antipsychotics, antiamnesics, and against other… 
2012
2012
1,4-Ditosyl-1,4-diazepane
In the title compound, C19H24N2O4S2, the dihedral angle formed by the benzene rings is 82.88 (7)°, and the molecular conformation… 
2011
2011
1,4-Diazepane compounds as potent and selective CB2 agonists: optimization of metabolic stability.
2011
2011
Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.
2011
2011
Methyl (9aR*,10S*,11R*,13aS*,13bS*)-9-oxo-6,7,9,9a,10,11-hexahydro-5H,13bH-11,13a-epoxypyrrolo[2′,1′:3,4][1,4]diazepino[2,1-a]isoindole-10-carboxylate
The title compound, C17H18N2O4, is the methyl ester of the adduct of intramolecular Diels–Alder reaction between maleic anhydride… 
2009
2009
User-friendly stereoselective one-pot access to 1,4-diazepane derivatives by a cyclodehydrative three-component reaction with 1,3-dicarbonyls.
A multicomponent reaction of 1,3-dicarbonyls with 1,2-diamines and aromatic aldehydes is described for the direct stereoselective… 
2006
2006
Asymmetric synthesis of 1-(2- and 3-haloalkyl)azetidin-2-ones as precursors for novel piperazine, morpholine, and 1,4-diazepane annulated beta-lactams.
A high-yielding, asymmetric synthesis of novel 4-formyl-1-(2- and 3-haloalkyl)azetidin-2-ones was developed as valuable starting… 
2004
2004
Synthesis and biological activity of novel 1,4-diazepane derivatives as factor Xa inhibitor with potent anticoagulant and antithrombotic activity.
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