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Synthesis and antimycobacterial activity of some 2-pyridinecarboxyamidrazone derivatives.
TLDR
A series of N1-aryliden-2-pyridincarboxyamidrazone derivatives showed interesting in vitro antimycobacterial activity against some strains of Mycobacterium and clinical isolates of Mycebacterium tuberculosis.
Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives.
TLDR
A three-dimensional pharmacophore model for the sigma(1) receptor binding site was developed using the Catalyst 4.9 software package and the best hypothesis, consisting of one positive ionizable, one hydrogen bond acceptor, two hydrophobic aromatic, and one hydrophilic features provided a 3D-QSAR model.
Simultaneous determination of amiodarone and desethylamiodarone in human plasma by high performance liquid chromatography.
A rapid, sensitive and specific reversed phase HPLC method for the simultaneous assay of amiodarone and its major metabolite desethylamiodarone in human serum has been developed. This method is
Synthesis and antibacterial activity of aminoguanidine and amidrazone derivatives
Synthese des composes du titre substitues par des aryl, pyridyl, pyrrolyl ou pyrimidinyl; activite antibacterienne in vitro
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