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1,3-oxathiolane

National Institutes of Health

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2015
2015
Chirality Control in Enzyme-Catalyzed Dynamic Kinetic Resolution of 1,3-Oxathiolanes.
The origin of enantioenrichment in enzyme-catalyzed dynamic kinetic resolution of 1,3-oxathiolane derivatives, key intermediates… 
2010
2010
Tandem 1,5-hydride shift/1,5-S,N-cyclization with ethylene extrusion of 1,3-oxathiolane-substituted ketenimines and carbodiimides. An experimental and computational study.
Under thermal activation in solution, N-[2-(1,3-oxathiolan-2-yl)]phenyl ketenimines and carbodiimides were converted into 2,1… 
2009
2009
1,3‐Dioxolane‐Based Ligands as Rigid Analogues of Naftopidil: Structure–Affinity/Activity Relationships at α1 and 5‐HT1A Receptors
Conformational restriction of naftopidil led to the discovery of a new class of ligands with a 1,3‐dioxolane (1,3‐oxathiolane, 1… 
2005
2005
Muscarinic subtype affinity and functional activity profile of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)pyrrolidine and 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine derivatives.
2004
2004
Synthesis and biological evaluation of 5R- and 5S-methyl substituted D- and L-configuration 1,3-dioxolane nucleoside analogs.
2003
2003
Synthesis and cholinergic affinity of diastereomeric and enantiomeric isomers of 1-methyl-2-(2-methyl-1,3-dioxolan-4-yl)- pyrrolidine, 1-methyl-2-(2-methyl-1,3-oxathiolan-5-yl)pyrrolidine and of…
1990
1990
Eudismic analysis of a series of muscarinic ligands carrying a 1,3-oxathiolane nucleus.
Eudismic analysis was performed on a set of 14 muscarinic ligands carrying a 1,3-oxathiolane nucleus, in order to obtain… 
1987
1987
Resolution, absolute configuration, and cholinergic enantioselectivity of (-)- and (+)-c-2-methyl-r-5-[(dimethylamino)methyl]-1,3-oxathiolane t-3-oxide methiodide and related sulfones.
As a continuation of previous studies on chiral cholinergic agonists carrying a 1,3-oxathiolane nucleus, the enantiomers of c-2… 
1985
1985
Cholinergic antagonists carrying a 1,3-oxathiolane nucleus
Synthese et activite biologique d'iodomethylates de dimethylaminomethyl-5 oxathiolannes-1,3 substituees en 2 
1984
1984
Size of muscarinic receptor anionic binding site related to onium group of ligands with a 1,3-oxathiolane nucleus
Synthese et activite de methyl-2 trialkylammoniomethyl-5 oxathiolannes-1,3 et de leurs derives oxyde-3 
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