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Coupling of I(1) imidazoline receptors to the cAMP pathway: studies with a highly selective ligand, benazoline.
- H. Greney, P. Rondé, M. Dontenwill
- BiologyMolecular pharmacology
- 1 June 2000
TLDR
Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity.
- M. Pigini, P. Bousquet, L. Brasili
- Biology, ChemistryBioorganic & medicinal chemistry
- 1 May 1997
Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.
- F. Gentili, P. Bousquet, M. Pigini
- ChemistryJournal of medicinal chemistry
- 22 May 2003
The alpha- and beta-methyl derivatives of 2-phenylethylimidazoline (compounds 7 and 8) and the corresponding enantiomers were prepared and tested with the purpose of studying the role played by the…
Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4-chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the…
- W. Quaglia, G. Santoni, M. Giannella
- Biology, ChemistryJournal of medicinal chemistry
- 2 November 2005
TLDR
Age-related changes in the density of muscarinic cholinergic M1 and M2 receptor subtypes in pyramidal neurons of the rat hippocampus.
- F. Amenta, A. Liu, M. Giannella, M. Pigini, S. Tayebati, D. Zaccheo
- BiologyEuropean journal of histochemistry : EJH
- 1995
TLDR
alpha 2-adrenoreceptors profile modulation. 2. Biphenyline analogues as tools for selective activation of the alpha 2C-subtype.
- F. Gentili, F. Ghelfi, A. Carrieri
- Chemistry, BiologyJournal of medicinal chemistry
- 2004
TLDR
α2C-adrenoceptor modulators: a patent review
- W. Quaglia, F. Del Bello, M. Giannella, A. Piergentili, M. Pigini
- BiologyExpert opinion on therapeutic patents
- 18 March 2011
TLDR
Antagonism/Agonism modulation to build novel antihypertensives selectively triggering i1-imidazoline receptor activation.
- F. Del Bello, V. Bargelli, M. Pigini
- Chemistry, BiologyACS medicinal chemistry letters
- 10 April 2015
TLDR
MOLECULAR REQUIREMENTS AT THE CHOLINERGIC RECEPTORS. IMPORTANCE OF ETHER OXYGENS IN THE DIOXOLANE SERIES
- C. Melchiorre, P. Angeli, L. Re
- Chemistry
- 26 December 1978
Pharmacophore development and 3D-QSAR study of I1 imidazoline binding site ligands
- O. Nicolotti, A. Carotti, M. Dontenwill
- Chemistry, Biology
- 1 April 2004
TLDR
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