• Corpus ID: 37079850

Synergistic effects of germ cell expressed genes on male fertility in mice.

@article{Nayernia2003SynergisticEO,
  title={Synergistic effects of germ cell expressed genes on male fertility in mice.},
  author={Karim Nayernia and Andreas Meinhardt and Birgit Drabent and Ibrahim M. Adham and Christian Müller and Michael Steckel and Ulrich Sancken and Wolfgang Engel},
  journal={Cytogenetic and genome research},
  year={2003},
  volume={103 3-4},
  pages={
          314-20
        },
  url={https://api.semanticscholar.org/CorpusID:37079850}
}
It was found that even when knockout mice are heterozygous for one allele (-/+) and homozygously for the other allele (-/-), mice were subfertile, indicating strongly that male germ cell expressed genes have synergistic effects on male fertility.
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9 Citations
Background Citations
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Methods Citations
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Results Citations
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9 Citations

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Genotyping of a large number of ALS patients and control subjects and combining the results with those from populations around the world revealed a dose-dependent association of the H63D HFE allele with sporadic ALS, and the association of this allele with other risk-associated alleles was explored.