Pulsed administration for physiological estrogen replacement in mice

@article{Corciulo2021PulsedAF,
  title={Pulsed administration for physiological estrogen replacement in mice},
  author={Carmen Corciulo and Julia M Scheffler and Karin L. Gustafsson and Christina Drevinge and Piotr Humeniuk and Alicia M Del Carpio Pons and Matti Poutanen and Claes Ohlsson and Marie K Lagerquist and Ulrika Islander},
  journal={F1000Research},
  year={2021},
  volume={10},
  url={https://api.semanticscholar.org/CorpusID:237240043}
}
Pulsed administration of physiological doses of E2 dissolved in miglyol rescues the phenotypes induced by OVX, and when E2 is dissolved in PBS the effects are less pronounced, possibly due to rapid wash out of the steroid.
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