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Endocrine-disrupting chemicals: an Endocrine Society scientific statement.
There is growing interest in the possible health threat posed by endocrine-disrupting chemicals (EDCs), which are substances in our environment, food, and consumer products that interfere withExpand
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Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional concepts in toxicology, in particular the dogma of "the dose makes the poison," because EDCs can have effectsExpand
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The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants.
Estrogens are defined by their ability to induce the proliferation of cells of the female genital tract. The wide chemical diversity of estrogenic compounds precludes an accurate prediction ofExpand
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Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption.
In 1991, a group of 21 scientists gathered at the Wingspread Conference Center to discuss evidence of developmental alterations observed in wildlife populations after chemical exposures. There, theExpand
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Developmental effects of endocrine-disrupting chemicals in wildlife and humans.
Large numbers and large quantities of endocrine-disrupting chemicals have been released into the environment since World War II. Many of these chemicals can disturb development of the endocrineExpand
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Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels.
The nonsteroidal estrogenic compound bisphenol A (BPA) is a monomer used in the manufacture of polycarbonate plastics and resins. BPA may be ingested by humans as it reportedly leaches from theExpand
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Estrogenicity of resin-based composites and sealants used in dentistry.
We tested some resin-based composites used in dentistry for their estrogenic activity. A sealant based on bisphenol-A diglycidylether methacrylate (bis-GMA) increased cell yields, progesteroneExpand
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Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society.
An endocrine-disrupting chemical (EDC) is an exogenous chemical, or mixture of chemicals, that can interfere with any aspect of hormone action. The potential for deleterious effects of EDC must beExpand
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Quantitative comparisons of in vitro assays for estrogenic activities.
Substances that may act as estrogens show a broad chemical structural diversity. To thoroughly address the question of possible adverse estrogenic effects, reliable methods are needed to detect andExpand
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An updated review of environmental estrogen and androgen mimics and antagonists
For the last 40 y, substantial evidence has surfaced on the hormone-like effects of environmental chemicals such as pesticides and industrial chemicals in wildlife and humans. The endocrine andExpand
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