Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites

@article{Pelliciari2017InsightIT,
  title={Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites},
  author={Simone Pelliciari and Eva M. Pinatel and Andrea Vannini and Clelia Peano and Simone Puccio and Gianluca De Bellis and Alberto Danielli and Vincenzo Scarlato and Davide Roncarati},
  journal={Scientific Reports},
  year={2017},
  volume={7},
  url={https://api.semanticscholar.org/CorpusID:9929500}
}
Using Chromatin Immunoprecipitation-sequencing (ChIP-seq), one of the most powerful approaches to characterize protein-DNA interactions in vivo, this work identified genome-wide several new HP1043 binding sites and revealed the presence of a conserved nucleotide sequence motif.
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Mutations to Essential Orphan Response Regulator HP1043 of Helicobacter pylori Result in Growth-Stage Regulatory Defects

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