Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues

@article{Logroscino2007DescriptiveEO,
  title={Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues},
  author={Giancarlo Logroscino and Bryan J. Traynor and Orla Hardiman and Adriano Chi{\`o} and Philippe Couratier and JOHN D. Mitchell and Robert J. Swingler and Ettore Beghi},
  journal={Journal of Neurology, Neurosurgery, and Psychiatry},
  year={2007},
  volume={79},
  pages={11 - 6},
  url={https://api.semanticscholar.org/CorpusID:26137341}
}
The contribution of the various population based registers is outlined, the limitations of the existing datasets are identified and a mechanism to improve the future design and output of descriptive epidemiological studies is proposed.
View on Publisher
ncbi.nlm.nih.gov
448 Citations
Highly Influential Citations
19
Background Citations
151
Methods Citations
7
Results Citations
26

448 Citations

Amyotrophic Lateral Sclerosis Descriptive Epidemiology: The Origin of Geographic Difference

The demographic changes related to increased expectation of life and the growth of the world population indicate that the load of motor neuron disease is rapidly moving toward 400 thousand prevalent cases and the burden is expected to shift toward Asia and Africa in the next decades for the rapid increase of expectation oflife of countries with high demographic impact.

Epidemiological and genetic features of amyotrophic lateral sclerosis in Latin America and the Caribbean: a systematic review

A systematic review of the epidemiology, frequency of genetic mutations, clinical characteristics and survival of ALS patients in Latin America highlights specific differences when comparing to Europe and North America.

Incidence and Prevalence of Amyotrophic Lateral Sclerosis in Canada: A Systematic Review of the Literature

A systematic review of published incidence and prevalence research in Canada found limited data on the frequency of ALS in Canada and found no studies from 6 of the Canadian provinces or from the territories.

Global Epidemiology of Amyotrophic Lateral Sclerosis: A Systematic Review of the Published Literature

Disparity in rates among ALS incidence and prevalence studies may be due to differences in study design or true variations in population demographics such as age and geography, including environmental factors and genetic predisposition.

Current pathways for epidemiological research in amyotrophic lateral sclerosis

This paper focuses on recent results from large-scale population based prospective studies, case-control studies and population based registries, risk factors, and neuropathologic findings in chronic traumatic encephalomyelopathy, and areas of interest for future research.

Amyotrophic lateral sclerosis: Analysis of ALS cases in a predominantly admixed population of Ecuador

Investigation in the predominantly admixed population of Ecuador found that ALS incidence in the Ecuadorian hospital population is in accord with rates reported in recent studies for other admixed populations, and lower than that in the United States and Europe.

Epidemiology of Amyotrophic Lateral Sclerosis: A Population-Based Study in Israel

There is a relatively high prevalence of ALS in Israel, and characteristics of ALS patients were compared to those of age-sex-matched patients without ALS in 2013, suggesting that factors that may contribute to the survival of patients withALS in Israel are needed.

Multicentre, prospective registry study of amyotrophic lateral sclerosis in mainland China (CHALSR): study protocol

The aim of this study was to explore the natural history and clinical features of ALS in mainland China through a multicentre, prospective cohort study, which will both offer a better understanding of ALS and also support the development of a model to study other rare diseases.

Amyotrophic Lateral Sclerosis Descriptive Studies: Not Only Rates and Frequencies

The reported prevalence in this study is around 5/100,000, lower than we expected based on other studies and the median survival of ALS patients. Similarly to the incidence, the prevalence peak is in…

The Epidemiology of Amyotrophic Lateral Sclerosis in New Hampshire, USA, 2004-2007

While localized areas in N.H. with high ALS incidence rates have been reported previously, the overall incidence and mortality rates are similar to those in other industrialized nations.
...

99 References

Amyotrophic lateral sclerosis mimic syndromes: a population-based study.

Clinical and demographic details of patients included in the Irish ALS Register who were incorrectly diagnosed as having ALS (patients who were ultimately rediagnosed as having an "ALS mimic syndrome") are described.

Epidemiology of ALS.

Associations of sporadic ALS with work in occupations that involve toxicant exposure and genetic susceptibility to environmental toxicants are identified; however, genetically acquired biochemical defects have not been identified in sporadic ALS patients.

Survival of Patients with Amyotrophic Lateral Sclerosis in a Population-Based Registry

Survival of ALS patients in the present sample was slightly longer than previously reported, and better palliative care and supportive treatment may explain the difference.

Incidence of amyotrophic lateral sclerosis in southern Italy: a population based study

ALS incidence is within a narrow range across countries, with a peak between 65 and 75 years and a higher incidence in men, and a north to south latitude gradient of ALS incidence is not supported by the results of cohort studies.

Riluzole and amyotrophic lateral sclerosis survival: a population‐based study in southern Italy

In this population‐based series, riluzole therapy improves ALS survival and is effective amongst cases with bulbar‐onset ALS and older patients, but not in subjects with limb-onset.

Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996–2000

Background: In recent years, there has been a paradigm shift in the method of healthcare delivery to amyotrophic lateral sclerosis (ALS) patients with the emergence of multidisciplinary ALS clinics…

Clinical features of amyotrophic lateral sclerosis according to the El Escorial and Airlie House diagnostic criteria: A population-based study.

The El Escorial and Airlie House diagnostic criteria for amyotrophic lateral sclerosis are excessively restrictive and levels of diagnostic certainty cannot be used as prognostic indicators.

Prognosis of amyotrophic lateral sclerosis and the effect of referral selection

Amyotrophic lateral sclerosis, heterogeneous susceptibility, trauma, and epidemiology.

The equations for the case-control odds ratio and cohort relative risk in populations with heterogeneous susceptibility to ALS converge as the proportion of ALS-nonsusceptable individuals in a population increases and the rate of ALS in nonsusceptible individuals decreases.

Amyotrophic lateral sclerosis care in Italy: a nationwide study in neurological centers

...