Incidence of amyotrophic lateral sclerosis in southern Italy: a population based study.

@article{Logroscino2005IncidenceOA,
  title={Incidence of amyotrophic lateral sclerosis in southern Italy: a population based study.},
  author={Giancarlo Logroscino and Ettore Beghi and Stefano Zoccolella and R Palagano and Angela Fraddosio and Isa Laura Simone and Paola Lamberti and Vito Lepore and Luigi Serlenga},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  year={2005},
  volume={76 8},
  pages={1094-8}
}
BACKGROUND While the incidence of amyotrophic lateral sclerosis (ALS) is similar across the world (range, 1.0 to 2.5/100,000), a latitude gradient from north to south has been observed. OBJECTIVE To determine the incidence of ALS in Puglia, a region of south eastern Italy, and to test the latitude gradient hypothesis comparing the present study with findings in studies conducted with the same design in a northern latitude. METHODS Puglia (4,086,613 residents in 2001) is the site of a… CONTINUE READING