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zoniporide

Known as: (1-(quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl)guanidine, N-Carbamimidoyl-5-cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Autoantibody production and immune complex deposition within the kidney promote renal disease in patients with lupus nephritis… Expand
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2013
2013
1. Aldehyde oxidase (AO) is a cytosolic enzyme that contributes to the Phase I metabolism of xenobiotics in human and preclinical… Expand
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2013
2013
It was discovered that a number of cyclin dependent kinase inhibitors containing the pyrazole core structure exhibited high… Expand
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2011
2011
The development of a second-generation process for the synthesis of eletriptan via a Fischer indole cyclisation is described. The… Expand
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Highly Cited
2010
Highly Cited
2010
Excretion and metabolism of zoniporide were investigated in humans after intravenous infusion of [14C]zoniporide at an 80-mg dose… Expand
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Review
2008
Review
2008
Extensive pre-clinical work indicates that inhibition of the Na(+)/H(+) exchanger (NHE) affords significant protection to… Expand
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2007
2007
Objective:To investigate whether sodium-hydrogen exchanger isoform-1 (NHE-1) inhibition attenuates myocardial injury during… Expand
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Highly Cited
2002
Highly Cited
2002
Abstract— The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high levels of mRNA expression… Expand
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Highly Cited
2001
Highly Cited
2001
The cardioprotective efficacy of zoniporide (CP-597,396), a novel, potent, and selective inhibitor of the sodium-hydrogen… Expand
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2001
2001
Zoniporide (CP-597,396) is a potent and selective inhibitor of NHE-1, which exhibits high aqueous solubility and acceptable… Expand
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