zoniporide

Known as: (1-(quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl)guanidine, N-Carbamimidoyl-5-cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
051020012017

Papers overview

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2013
2013
1. Aldehyde oxidase (AO) is a cytosolic enzyme that contributes to the Phase I metabolism of xenobiotics in human and preclinical… (More)
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2012
2012
A series of N,1,3-triphenyl-1H-pyrazole-4-carboxamide derivatives have been designed, synthesized and evaluated for their… (More)
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2010
2010
Excretion and metabolism of zoniporide were investigated in humans after intravenous infusion of [(14)C]zoniporide at an 80-mg… (More)
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2008
2008
Zoniporide, an inhibitor of the Na+-H+ exchanger-1, was administered by continuous intravenous infusion to rats and dogs for up… (More)
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2007
2007
OBJECTIVE To investigate whether sodium-hydrogen exchanger isoform-1 (NHE-1) inhibition attenuates myocardial injury during… (More)
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2005
2005
OBJECTIVES To determine whether a novel Na+/H+ exchange ion inhibitor, zoniporide, is associated with reduced perioperative… (More)
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Highly Cited
2002
Highly Cited
2002
The orphan receptor APJ and its recently identified endogenous ligand, apelin, exhibit high levels of mRNA expression in the… (More)
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2002
2002
We evaluated the in vitro pharmacological profile of a novel, potent and highly selective Na(+)/H(+) exchanger-1 (NHE-1… (More)
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2001
2001
The cardioprotective efficacy of zoniporide (CP-597,396), a novel, potent, and selective inhibitor of the sodium-hydrogen… (More)
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2001
2001
Zoniporide (CP-597,396) is a potent and selective inhibitor of NHE-1, which exhibits high aqueous solubility and acceptable… (More)
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