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zoledronate

Known as: (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid, [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic Acid, NDC-Zoledronate 
The brand name for zoledronic acid, a bisphosphonic imidazol compound which inhibits osteoclastic bone resorption. Although its mechanisms of action… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (4)

CGP 42446AZOL 446Zometazoledronic acid anhydrous
Pamidronate Disodiumcalcitriol/zoledronatecalcium carbonate/cholecalciferol/zoledronatedoxorubicin/goserelin/zoledronate
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Broader (1)

zoledronic acid

Papers overview

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Review
2017
Review
2017
Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT…
Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading… Expand
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Review
2016
Review
2016
Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial.
BACKGROUND Based on preclinical data for the antitumour effect of zoledronate in osteosarcoma, we assessed whether zoledronate… Expand
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Highly Cited
2013
Highly Cited
2013
Zoledronic acid (zoledronate) for postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study): final 60-month results.
BACKGROUND Aromatase inhibitors are the preferred adjuvant endocrine therapy for the majority of postmenopausal women with… Expand
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Highly Cited
2008
Highly Cited
2008
Zoledronate, smoking, and obesity are strong risk factors for osteonecrosis of the jaw: a case-control study.
PURPOSE Bisphosphonates (BPs) effectively treat metastatic bone disease, hypercalcemia, and osteoporosis. BP exposure, however… Expand
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Highly Cited
2008
Highly Cited
2008
Zoledronate facilitates large-scale ex vivo expansion of functional gammadelta T cells from cancer patients for use in adoptive immunotherapy.
BACKGROUND Human gammadelta T cells can be activated by phospho-antigens and aminobisphosphonates such as zoledronate. Because… Expand
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Highly Cited
2007
Highly Cited
2007
Targeting human {gamma}delta} T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer.
The increasing evidence that gammadelta T cells have potent antitumor activity suggests their value in immunotherapy… Expand
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Review
2007
Review
2007
Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy
SummaryBisphosphonates (BPs) are well established as the leading drugs for the treatment of osteoporosis. There is new knowledge… Expand
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Highly Cited
2003
Highly Cited
2003
Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic.
  • Robert E. Marx
  • Journal of oral and maxillofacial surgery…
  • 2003
    • Corpus ID: 13516453
 
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Highly Cited
2003
Highly Cited
2003
Toxic acute tubular necrosis following treatment with zoledronate (Zometa).
BACKGROUND Renal failure and toxic acute tubular necrosis (ATN) may be seen following exposure to a variety of therapeutic agents… Expand
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Highly Cited
1998
Highly Cited
1998
Non-chondritic meteorites from asteroidal bodies
Zolensky ME, and McSween, HY Jr (1988) Aqueous alteration. In Meteorites and the Early Solar System (JF KCITIdge, MS Matthews cds… Expand
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