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zoledronate
Known as:
(1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid
, [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic Acid
, NDC-Zoledronate
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The brand name for zoledronic acid, a bisphosphonic imidazol compound which inhibits osteoclastic bone resorption. Although its mechanisms of action…
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National Institutes of Health
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Related topics
Related topics
11 relations
Narrower (4)
CGP 42446A
ZOL 446
Zometa
zoledronic acid anhydrous
Pamidronate Disodium
calcitriol/zoledronate
calcium carbonate/cholecalciferol/zoledronate
doxorubicin/goserelin/zoledronate
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Broader (1)
zoledronic acid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The why, when and how to test for obstructive sleep apnea in patients with atrial fibrillation
L. Desteghe
,
J. Hendriks
,
+6 authors
D. Linz
Clinical Research in Cardiology
2018
Corpus ID: 4794063
Sleep apnea is associated with increased cardiovascular risk and may be important in atrial fibrillation (AF) management. It is…
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2013
2013
Variations in nanomechanical properties and tissue composition within trabeculae from an ovine model of osteoporosis and treatment.
J. Burket
,
Daniel J. Brooks
,
J. MacLeay
,
S. Baker
,
A. Boskey
,
M. V. D. van der Meulen
Bone
2013
Corpus ID: 20442199
2007
2007
Anabolic effects of bisphosphonates on peri-implant bone stock.
F. von Knoch
,
C. Eckhardt
,
Claude I Alabre
,
E. Schneider
,
H. Rubash
,
A. Shanbhag
Biomaterials
2007
Corpus ID: 9633879
Highly Cited
2005
Highly Cited
2005
Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells
C. Chuah
,
D. J. Barnes
,
+4 authors
J. Melo
Leukemia
2005
Corpus ID: 36276182
Although imatinib mesylate has revolutionized the treatment of chronic myeloid leukaemia (CML), resistance to the drug…
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Highly Cited
2005
Highly Cited
2005
Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer.
Sun-jin Kim
,
H. Uehara
,
+5 authors
I. Fidler
Cancer Research
2005
Corpus ID: 16488969
Prostate cancer cells metastasize to the bone where their interaction with osteoclasts and osteoblasts can lead to alterations in…
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Highly Cited
2004
Highly Cited
2004
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the…
U. Vogt
,
K. Bielawski
,
U. Bosse
,
C. Schlotter
Oncology Report
2004
Corpus ID: 5813621
Breast cancer has a significant capacity to metastasize to bone. Bisphosphonates are the standard treatment for hypocalcaemia of…
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2004
2004
Zoledronic acid up-regulates bone sialoprotein expression in osteoblastic cells through Rho GTPase inhibition.
M. Chaplet
,
C. Detry
,
C. Deroanne
,
L. Fisher
,
V. Castronovo
,
A. Bellahcène
Biochemical Journal
2004
Corpus ID: 29391624
Clinical practice reveals that osteoporotic women treated with BPs (bisphosphonates) show an increased bone mass density and a…
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Review
2001
Review
2001
Analysis of skeletal-related events in breast cancer and response to therapy.
Patricia M. LoRusso
Seminars in Oncology
2001
Corpus ID: 23518041
Highly Cited
2000
Highly Cited
2000
Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines
P. Tassone
,
S. Forciniti
,
+5 authors
Salvatore Venuta
Leukemia
2000
Corpus ID: 6173876
Bisphosphonates (BPs) are commonly used in the treatment of myeloma-associated osteolytic lesions. Recent reports have suggested…
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1993
1993
Liarozole and 13-cis-retinoic acid anti-prostatic tumor activity.
M. Stearns
,
M. Wang
,
K. Fudge
Cancer Research
1993
Corpus ID: 8360290
Liarozole fumarate (R85,246), a novel benzimidazole derivative, reduced s.c. and bone metastasis tumor growth by the androgen…
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