zinc-exporting ATPase activity

Known as: Zn2+-exporting ATPase activity, Zn(II)-translocating P-type ATPase activity, zinc exporting ATPase activity 
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP… (More)
National Institutes of Health

Papers overview

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2014
2014
Regulation of the Catabolic Cascade in Osteoarthritis by the Zinc-ZIP8-MTF1 Axis
Osteoarthritis (OA), primarily characterized by cartilage degeneration, is caused by an imbalance between anabolic and catabolic… (More)
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2011
2011
Tandem Quadruplication of HMA4 in the Zinc (Zn) and Cadmium (Cd) Hyperaccumulator Noccaea caerulescens
Zinc (Zn) and cadmium (Cd) hyperaccumulation may have evolved twice in the Brassicaceae, in Arabidopsis halleri and in the… (More)
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2009
2009
A common highly conserved cadmium detoxification mechanism from bacteria to humans: heavy metal tolerance conferred by the ATP-binding cassette (ABC) transporter SpHMT1 requires glutathione but not…
Cadmium poses a significant threat to human health due to its toxicity. In mammals and in bakers' yeast, cadmium is detoxified by… (More)
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Highly Cited
2006
Highly Cited
2006
Zinc-dependent global transcriptional control, transcriptional deregulation, and higher gene copy number for genes in metal homeostasis of the hyperaccumulator Arabidopsis halleri.
The metal hyperaccumulator Arabidopsis halleri exhibits naturally selected zinc (Zn) and cadmium (Cd) hypertolerance and… (More)
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2006
2006
The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide.
The retromer complex is involved in the retrograde transport of the CI-M6PR (cation-independent mannose 6-phosphate receptor… (More)
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2005
2005
Heavy metal transport by AtHMA4 involves the N-terminal degenerated metal binding domain and the C-terminal His11 stretch.
The Arabidopsis thaliana AtHMA4 is a P1B-type ATPase that clusters with the Zn/Cd/Pb/Co subgroup. It has been previously shown… (More)
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2005
2005
The plant P1B-type ATPase AtHMA4 transports Zn and Cd and plays a role in detoxification of transition metals supplied at elevated levels.
The transition metal Zn is essential for many physiological processes in plants, yet at elevated concentrations this, and the… (More)
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Highly Cited
2004
Highly Cited
2004
Overexpression of AtHMA4 enhances root-to-shoot translocation of zinc and cadmium and plant metal tolerance.
AtHMA4 is an Arabidopsis thaliana P1B-ATPase which transports Zn and Cd. Here, we demonstrate that AtHMA4 is localized at the… (More)
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Highly Cited
2004
Highly Cited
2004
A novel CPx-ATPase from the cadmium hyperaccumulator Thlaspi caerulescens.
Thlaspi caerulescens exhibits a unique capacity for cadmium tolerance and accumulation. We investigated the molecular basis of… (More)
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Highly Cited
2003
Highly Cited
2003
Functional expression of AtHMA4, a P1B-type ATPase of the Zn/Co/Cd/Pb subclass.
Mechanisms are required by all organisms to maintain the concentration of essential heavy metals (e.g. Zn and Cu) within… (More)
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