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zetekitoxin AB

Known as: zetekitoxin 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Saxitoxin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A Direct C11 Alkylation Strategy on the Saxitoxin Core: A Synthesis of (+)-11-Saxitoxinethanoic Acid.
The bis-guanidinium ion family of natural products are revered for their utility in the study of ion channel physiology. While… Expand
Review
2019
Review
2019
Synthetic Approaches to Zetekitoxin AB, a Potent Voltage-Gated Sodium Channel Inhibitor
Voltage-gated sodium channels (NaVs) are membrane proteins that are involved in the generation and propagation of action… Expand
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2015
2015
Preparation of a 1,2-isoxazolidine synthon for the synthesis of zetekitoxin AB.
A synthesis of the 1,2-isoxazolidine fragment of the potent voltage gated sodium channel blocker, zetekitoxin AB is described… Expand
2014
2014
Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol.
A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach… Expand
2010
2010
First report on toxins in the Panamanian toads Atelopus limosus, A. glyphus and A. certus.
Major toxins from skin extracts of 18 specimens of six Atelopus toad species collected in Panama were analyzed. Chiriquitoxin was… Expand
2006
2006
ILI-5 Potent Neurotoxin of Chiriquitoxin and Zetekitoxin from the Panamanian Golden Frogs Atelopus Species(Isolation and Structure Elucidation of Natural Products)
 
2006
2006
An efficient total synthesis of optically active tetrodotoxin and synthetic studies of zetekitoxin AB, isolated from Panamanian dart frog
 
Highly Cited
2004
Highly Cited
2004
The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker.
Bufonid anurans of the genus Atelopus contain both steroidal bufadienolides and various guanidinium alkaloids of the tetrodotoxin… Expand
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1977
1977
Chemistry and pharmacology of skin toxins from the frog Atelopus zeteki (atelopidtoxin: zetekitoxin).
Abstract Chemistry and pharmacology of skin toxins from the frog Atelopus zeteki (atelopidtoxin; zetekitoxin). Toxicon 15, 115… Expand
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