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zatebradine

Known as: UL-FS49 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzazepinesCardiotonic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Development of correction formula for field potential duration of human induced pluripotent stem cell-derived cardiomyocytes sheets.
Highly Cited
2006
Highly Cited
2006
Bradycardic and Proarrhythmic Properties of Sinus Node Inhibitors
Sinus node inhibitors reduce the heart rate presumably by blocking the pacemaker current If in the cardiac conduction system… 
Review
2002
Review
2002
In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: application to the preclinical cardiovascular safety pharmacology of a new chemical entity
In addition to in silico and in vitro measurements, cardiac electrophysiology in experimental animals plays a decisive role in… 
1999
1999
Effects of blocking the hyperpolarization-activated current (I h) on the cat electroretinogram
1997
1997
Force-frequency relations in the failing rabbit heart and responses to adrenergic stimulation.
Highly Cited
1996
Highly Cited
1996
Class III antiarrhythmic effects of zatebradine. Time-, state-, use-, and voltage-dependent block of hKv1.5 channels.
BACKGROUND Zatebradine is a bradycardic agent that inhibits the hyperpolarization-activated current (I(f)) in the rabbit… 
1994
1994
Specific bradycardic agents block the hyperpolarization-activated cation current in central neurons
Highly Cited
1994
Highly Cited
1994
Myofibrillar Ca2+ Sensitization Predominantly Enhances Function and Mechanical Efficiency of Stunned Myocardium
BackgroundMyocardial stunning is characterized not only by a decreased regional postischemic function but also by a relatively… 
1993
1993
Zatebradine: pharmacokinetics of a novel heart-rate-lowering agent after intravenous infusion and oral administration to healthy subjects.
Zatebradine (1; UL-FS 49 CL; 1,3,4,5-[tetrahydro-7,8-dimethoxy-3-[3-[ [2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-2H-3… 
1992
1992
Blockade of the pacemaker current by intracellular application of UL-FS 49 and UL-AH 99 in sheep cardiac Purkinje fibers.
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