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yuanhuadine

National Institutes of Health

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Terpenes

Papers overview

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2018
2018
Targeting Nicotinamide N-Methyltransferase and miR-449a in EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Cells
2018
2018
BMP4 Upregulation Is Associated with Acquired Drug Resistance and Fatty Acid Metabolism in EGFR-Mutant Non-Small-Cell Lung Cancer Cells
2017
2017
Daphnane and Phorbol Diterpenes, Anti-neuroinflammatory Compounds with Nurr1 Activation from the Roots and Stems of Daphne genkwa.
The methanol extract of the roots and stems of Daphne genkwa and its constituents yuanhuacin (1) and genkwanine N were previously… 
2016
2016
Down-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions
The failure of targeted therapy due to the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs… 
Highly Cited
2015
Highly Cited
2015
Targeting the degradation of AXL receptor tyrosine kinase to overcome resistance in gefitinib-resistant non-small cell lung cancer
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, remains a… 
Highly Cited
2011
Highly Cited
2011
Growth inhibition of human lung cancer cells via down-regulation of epidermal growth factor receptor signaling by yuanhuadine, a daphnane diterpene from Daphne genkwa.
The growth inhibition and antitumor activities of yuanhuadine (1), a daphnane diterpenoid from the flowers of Daphne genkwa, were… 
Highly Cited
2010
Highly Cited
2010
Daphnane diterpene esters with anti-proliferative activities against human lung cancer cells from Daphne genkwa.
Two new daphnane-type diterpene esters, yuanhuahine (1) and yuanhualine (2), were isolated from the flowers of Daphne genkwa… 
Highly Cited
2006
Highly Cited
2006
Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure-activity relationship of potent inhibitory activity against DNA topoisomerase I.
Review
1987
Review
1987
Important Chinese herbal remedies.
  • G. Ding
  • Clinical Therapeutics
  • 1987
  • Corpus ID: 36758288
This review presents seven examples of effective drugs derived from the ancient Chinese therapeutics. They are artemisinin… 
1981
1981
STUDIES ON THE ACTIVE PRINCIPLES OF THE ROOT OF YUAN-HUA (DAPHNE GENKWA) II. ISOLATION AND STRUCTURE OF A NEW ANTIFERTILE DITERPENE YUANHUADINE
A new diterpene orthoester, Yuanhuadine C_(32)H_(42)O_(10), M~+m/z 586.2790, [a]_D~(16.5)+26.9°(c. 0.045 CHCl_3)was isolated from… 
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