yuanhuadine
National Institutes of Health
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The methanol extract of the roots and stems of Daphne genkwa and its constituents yuanhuacin (1) and genkwanine N were previously…
The failure of targeted therapy due to the resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs…
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib, remains a…
The growth inhibition and antitumor activities of yuanhuadine (1), a daphnane diterpenoid from the flowers of Daphne genkwa, were…
Two new daphnane-type diterpene esters, yuanhuahine (1) and yuanhualine (2), were isolated from the flowers of Daphne genkwa…
This review presents seven examples of effective drugs derived from the ancient Chinese therapeutics. They are artemisinin…
A new diterpene orthoester, Yuanhuadine C_(32)H_(42)O_(10), M~+m/z 586.2790, [a]_D~(16.5)+26.9°(c. 0.045 CHCl_3)was isolated from…