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wybutine

National Institutes of Health

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wye

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2012
2012
Structural significance of hypermodified nucleic acid base hydroxywybutine (OHyW) which occur at 37th position in the anticodon loop of yeast tRNA(Phe).
2005
2005
tRNAPhe cleavage by aminoglycosides is triggered off by formation of an abasic site.
Highly Cited
2004
Highly Cited
2004
Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions.
The anticodon loop of tRNA contains a number of conserved or semiconserved nucleotides. In most tRNAs, a highly modified purine… 
2004
2004
Conformational dynamics of the anticodon loop in yeast tRNAPhe as sensed by the fluorescence of wybutine
Conformational and dynamic properties of the anticodon loop of yeast tRNAPhe were investigated by analyzing the time resolved… 
Highly Cited
1986
Highly Cited
1986
Pre-steady-state kinetics of ribosomal translocation.
1986
1986
tRNA topography during translocation: steady-state and kinetic fluorescence energy-transfer studies.
The distances between the anticodon loops of fluorescent tRNAPhe bound to the E site and to either the A or the P site of poly(U… 
Highly Cited
1983
Highly Cited
1983
Topological arrangement of two transfer RNAs on the ribosome. Fluorescence energy transfer measurements between A and P site-bound tRNAphe.
1982
1982
Effect of ribosome binding and translocation on the anticodon of tRNAPhe as studied by wybutine fluorescence.
The complexes of N-AcPhe-tRNAPhe (or non-aminoacylated tRNAPhe) from yeast with 70S ribosomes from E. coli have been studied… 
1979
1979
On the structure and conformational dynamics of yeast phenylalanine-accepting transfer ribonucleic acid in solution.
The solution structure of yeast tRNAPhe was investigated by using ethidium as a fluorescent probe in the D loop and the anticodon… 
1978
1978
Replacement of wybutine by hydrazines and its effect on the active conformation of yeast tRNAPhe.
The highly modified base wybutine (YWye) next to the anticodon of yeast tRNAPhe has been replaced by different hydrazine… 
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