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wybutine

National Institutes of Health

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wye

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2012
2012
Structural significance of hypermodified nucleic acid base hydroxywybutine (OHyW) which occur at 37th position in the anticodon loop of yeast tRNA(Phe).
2005
2005
Fluorimetric study of yeast tRNAPheCCF in the complex with phenylalanyl-tRNA synthetase. Evidence for a correlation between the structural adaptation of both macromolecules and the appearance of the…
The fluorescence properties of yeast tRNAPheCCF (tRNAPhe in which the 3'-terminal adenosine has been replaced by formycin) and… 
2004
2004
Conformational dynamics of the anticodon loop in yeast tRNAPhe as sensed by the fluorescence of wybutine
Conformational and dynamic properties of the anticodon loop of yeast tRNAPhe were investigated by analyzing the time resolved… 
2004
2004
Theoretical Analysis of the Excited State Properties of Wybutine: A Natural Probe for Transfer RNA Dynamics
We have theoretically characterized the ground state and the excited state properties of wybutine, a naturally fluorescent… 
1986
1986
tRNA topography during translocation: steady-state and kinetic fluorescence energy-transfer studies.
The distances between the anticodon loops of fluorescent tRNAPhe bound to the E site and to either the A or the P site of poly(U… 
1984
1984
Crosslinking transfer RNA and messenger RNA at the ribosomal decoding region: identification of the site of reaction on the messenger RNA.
Wybutine (Ywye), situated next to the 3'-side of the anticodon of tRNAPhe from Saccharomyces cerevisiae, can be photo-crosslinked… 
Highly Cited
1983
Highly Cited
1983
Topological arrangement of two transfer RNAs on the ribosome. Fluorescence energy transfer measurements between A and P site-bound tRNAphe.
1982
1982
Conformational activation of aminoacyl-tRNA synthetases upon binding of tRNA. A facet of a multi-step adaptation process leading to the optimal biological activity.
The activation of the catalytic center of aminoacyl-tRNA synthetases upon binding of the tRNA, previously reported in the case of… 
1980
1980
Mechanism of translocation: relative arrangement of tRNA and mRNA on the ribosome.
AcPhe-tRNAPhe from yeast can be photocross-linked to poly(U) on Escherichia coli ribosomes. The photoreaction occurs at the… 
1979
1979
On the structure and conformational dynamics of yeast phenylalanine-accepting transfer ribonucleic acid in solution.
The solution structure of yeast tRNAPhe was investigated by using ethidium as a fluorescent probe in the D loop and the anticodon… 
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