willardiine

Known as: (S)-alpha-amino-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine propanoic acid, 3-(Uracil-1-yl)-L-alanine, beta-(2,4-dihydroxypyrimidin-1-yl)alanine 
 

Topic mentions per year

Topic mentions per year

1965-2014
012319652014

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Ionotropic glutamate receptors mediate the majority of vertebrate excitatory synaptic transmission. The development of selective… (More)
Is this relevant?
2007
2007
Some N3-substituted analogues of willardiine such as 11 and 13 are selective kainate receptor antagonists. In an attempt to… (More)
Is this relevant?
2006
2006
N3-substitution of the uracil ring of willardiine with a variety of carboxyalkyl or carboxybenzyl substituents produces AMPA and… (More)
Is this relevant?
2005
2005
The natural product willardiine (8) is an AMPA receptor agonist while 5-iodowillardiine (10) is a selective kainate receptor… (More)
Is this relevant?
2004
2004
Willardiine derivatives with an N3-benzyl substituent bearing an acidic group have been synthesized with the aim of producing… (More)
Is this relevant?
2003
2003
1. The natural product willardiine is an AMPA receptor agonist. We have examined the structural changes required to convert… (More)
Is this relevant?
1997
1997
Both willardiine and azawillardiine analogs (18-28) have been reported to be potent and selective agonists for either AMPA or… (More)
Is this relevant?
1994
1994
Concentration jump responses to 5-substituted (S)-willardiines were recorded from dorsal root ganglion (DRG) and hippocampal… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1992
1992
Willardiine [(S)-1-(2-amino-2-carboxyethyl)pyrimidine-2,4-dione] is a naturally occurring heterocyclic excitatory amino acid… (More)
  • figure 2
  • figure 1
  • table 1
  • figure 3
  • figure 4
Is this relevant?
1972
1972
The synthesis of the pyrimidinyl amino acids willardiine and isowillardiine was studied in vivo and in vitro. Uracil derivatives… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?