Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

willardiine

Known as: (S)-alpha-amino-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine propanoic acid, 3-(Uracil-1-yl)-L-alanine, beta-(2,4-dihydroxypyrimidin-1-yl)alanine 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Progress in understanding the roles of kainate receptors (KARs) in synaptic integration, synaptic networks, and higher brain… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
Ionotropic glutamate receptors mediate the majority of vertebrate excitatory synaptic transmission. The development of selective… Expand
Is this relevant?
2007
2007
Some N3-substituted analogues of willardiine such as 11 and 13 are selective kainate receptor antagonists. In an attempt to… Expand
Is this relevant?
2006
2006
N3-substitution of the uracil ring of willardiine with a variety of carboxyalkyl or carboxybenzyl substituents produces AMPA and… Expand
Is this relevant?
2005
2005
The natural product willardiine (8) is an AMPA receptor agonist while 5-iodowillardiine (10) is a selective kainate receptor… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Willardiine derivatives with an N3-benzyl substituent bearing an acidic group have been synthesized with the aim of producing… Expand
Is this relevant?
1998
1998
Characterization of the role of kainate receptors in excitatory synaptic transmission has been hampered by a lack of subtype… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1997
1997
Both willardiine and azawillardiine analogs (18-28) have been reported to be potent and selective agonists for either AMPA or… Expand
Is this relevant?
1994
1994
Concentration jump responses to 5-substituted (S)-willardiines were recorded from dorsal root ganglion (DRG) and hippocampal… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
1992
1992
Willardiine [(S)-1-(2-amino-2-carboxyethyl)pyrimidine-2,4-dione] is a naturally occurring heterocyclic excitatory amino acid… Expand
  • figure 2
  • figure 1
  • table 1
  • figure 3
  • figure 4
Is this relevant?