vindoline

Known as: (2 beta,3 beta,4 beta,5 alpha,12 beta,19 alpha)- 4-(acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy- 1-methylaspidospermidine-3-carboxylic acid, (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylic acid 
An indole alkaloid that exhibits antimitotic activity by inhibiting microtubule assembly. (NCI)
National Institutes of Health

Papers overview

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2015
2015
Antitumor substances related to vinblastine and vincristine are exclusively found in the Catharanthus roseus (Madagascar… (More)
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2011
2011
Vindoline constitutes the main terpenoid indole alkaloid accumulated in leaves of Catharanthus roseus, and four genes involved in… (More)
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2010
2010
A concise asymmetric total synthesis of (-)-vindoline (1) is detailed based on a tandem intramolecular [4+2]/[3+2] cycloaddition… (More)
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2009
2009
Catharanthuse roseus is a well-known medicinal plant for its two valuable anticancer compounds: vinblastine and vincristine… (More)
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2008
2008
Suspension cultures of Catharanthus roseus were used to evaluate ultraviolet-B (UV-B) treatment as an abiotic elicitor of… (More)
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Highly Cited
2008
Highly Cited
2008
Catharanthus roseus is the sole commercial source of the monoterpenoid indole alkaloids (MIAs), vindoline and catharanthine… (More)
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Highly Cited
2004
Highly Cited
2004
A comprehensive metabolomic profiling of Catharanthus roseus L. G. Don infected by 10 types of phytoplasmas was carried out using… (More)
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2002
2002
Catharanthus roseus cell cultures were exposed to different conditions in order to induce alkaloid metabolism. The exposure to… (More)
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Highly Cited
1988
Highly Cited
1988
Multidrug resistance (MDR), typified by resistance to Vinca alkaloids and anthracyclines, is a well characterized experimental… (More)
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Review
1963
Review
1963
A phytochemical investigation of the plant Vinca ro@eaLinn. has demonstrated that a number of alkaloidal substances can be… (More)
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