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vertilmicin

 
National Institutes of Health

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Aminoglycosides

Papers overview

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2015
2015
Evaluation of in vitro synergy between vertilmicin and ceftazidime against Pseudomonas aeruginosa using a semi-mechanistic pharmacokinetic/pharmacodynamic model.
The aim of this study was to develop a semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) model to evaluate the in vitro… Expand
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2013
2013
Analysis of impurities in vertilmicin sulfate by liquid chromatography ion-trap mass spectrometry.
The characterization of impurities present in vertilmicin by liquid chromatography (LC) coupled with mass spectrometry (MS) is… Expand
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2010
2010
Pharmacokinetics of vertilmicin, a novel aminoglycoside antibiotic, in rats and dogs
The pharmacokinetics of vertilmicin was investigated in rats and dogs following intramuscular or intravenous administration of… Expand
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2009
2009
In vivo antibacterial activity of vertilmicin, a new aminoglycoside antibiotic.
Vertilmicin is a novel aminoglycoside antibiotic with potent activity against gram-negative and -positive bacteria in vitro. In… Expand
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2008
2008
In vitro antibacterial activity of vertilmicin and its susceptibility to modifications by the recombinant AAC6'-APH2'' enzyme.
Vertilmicin is a new semisynthetic aminoglycoside with a structure similar to that of netilmicin except for a methyl group at the… Expand
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2006
2006
Determination of vertilmicin sulfate and its related substances by HPLC-ELSD and HPLC-MS2.
A new and simple high-performance liquid chromatography (HPLC)-evaporative light scattering detection (ELSD) method for the… Expand
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2006
2006
High performance liquid chromatography for the determination of glucosamine sulfate in human plasma after derivatization with 9-fluorenylmethyl chloroformate.
In this study, we developed a simple, rapid, sensitive, and reliable method for the determination of glucosamine sulfate in human… Expand
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2005
2005
High-performance liquid chromatographic determination of vertilmicin in rat plasma using sensitive fluorometric derivatization.
A sensitive and reliable high-performance liquid chromatographic method was developed for the determination of vertilmicin in rat… Expand
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2005
2005
Stability indicating reversed-phase ion-pairing liquid chromatographic determination of vertilmicin sulfate as bulk drug and in injections.
A simple reversed-phase high performance liquid chromatographic method was developed for the analysis of vertilmicin sulfate, a… Expand
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2003
2003
Determination of vertilmicin in rat serum by high-performance liquid chromatography using 1-fluoro-2,4-dinitrobenzene derivatization.
A procedure for the high-performance liquid chromatographic determination of vertilmicin in rat serum was described using pre… Expand
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