vardenafil

Known as: Vardenafilum, Vardénafil, 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-F][1,2,4]triazin-4(1H)-one 
A benzenesulfonamide derivative and phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Vardenafil selectively inhibits PDE5, thus… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
To date, studies suggest that biological signaling by nitric oxide (NO) is primarily mediated by cGMP, which is synthesized by NO… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND To date, no data have been available from large, well-designed trials comparing on demand and nightly dosing of… (More)
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Highly Cited
2008
Highly Cited
2008
INTRODUCTION Benign prostatic hyperplasia (BPH) is associated with bothersome lower urinary tract symptoms (LUTS) and reduced… (More)
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Highly Cited
2007
Highly Cited
2007
Benign prostate hyperplasia is the most common disease in the aging male, often comorbid with erectile dysfunction… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVES Impotence, specifically corporal veno-occlusive dysfunction (CVOD), occurs after radical prostatectomy. It results… (More)
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Highly Cited
2006
Highly Cited
2006
Phosphodiesterase-5 (PDE5) inhibitors (sildenafil, tadalafil, and vardenafil) are agents currently in clinical use for… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE This study evaluated the efficacy and safety of vardenafil treatment for erectile dysfunction (ED) in men with diabetes… (More)
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Highly Cited
2001
Highly Cited
2001
Vardenafil, a novel selective phosphodiesterase type 5 inhibitor, was evaluated in its first large-scale at-home trial. A total… (More)
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Highly Cited
2001
Highly Cited
2001
We investigated the potency and the selectivity profile of vardenafil on phosphodiesterase (PDEs) enzymes, its ability to modify… (More)
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Highly Cited
2001
Highly Cited
2001
The pharmacodynamic effect on penile rigidity and tumescence and the pharmacokinetic properties of single oral doses of 10 and 20… (More)
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