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urolithin A

National Institutes of Health

Papers overview

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2019
2019
Abstract 2971: Ellagic acid and its metabolite Urolithin A induce prostate cancer cell death in p53 dependent and independent manner
Carcinoma of the prostate (CaP) is the most common cancer in men and the second leading cause of cancer-related death in men… 
2019
2019
Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19)
Muscle health declines with aging and is accompanied by impairment of skeletal muscle mitochondrial function. Strategies… 
2019
2019
Urolithin A, a Gut Metabolite, Induces Metabolic Reprogramming of Adipose Tissue by Promoting M2 Macrophage Polarization and Mitochondrial Function (OR12-02-19).
Objectives Macrophage polarization into pro-inflammatory M1 status is associated with the pathologic progression of adipose… 
2018
2018
Ellagic Acid and Urolithin A Improve Insulin Sensitivity in Diet-Induced Insulin Resistant Mice and Reduce Detrimental Effects of Palmitate Administration in Differentiated C2C12 Myotubes.
Author(s): Chan, Brenda | Advisor(s): Clarke, Catherine F. | Abstract: Insulin resistance has been spreading as food and… 
2018
2018
Ellagic Acid and Urolithin A Improve Insulin Sensitivity in Diet-Induced Insulin Resistant Mice and Reduce Detrimental Effects of Palmitate Administration in Differentiated C2C12 Myotubes
.......................................................................................................................................... ii Committee Members ...................................................................................................................... iv Dedication ........................................................................................................................................v Table of 
2017
2017
but not iso-Urolithin A and Urolithin B , attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes 1
2017
2017
Abstract 5259: Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling
Pancreatic ductal adenocarcinoma (PDAC) is the 3rd leading cause of cancer-related mortality in the United States. Most patients… 
2015
2015
Abstract 4651: Urolithin A (UA) inhibits both androgen receptor and AKT signaling and prevents the progression of castration resistant prostate cancer
Current therapeutic regimens are insufficient for treating advanced and metastatic prostate cancer. Compelling evidence suggest… 
2012
2012
Pomegranate ellagitannin metabolite, Urolithin A, inhibits prostate cancer cell proliferation via inhibition of IGF‐1 signaling pathway
Colonic microflora convert pomegranate ellagitannins (ETs) to ellagic acid (EA) and urolithins, primarily Urolithin A (UA). We… 
2007
2007
Pharmacokinetics and tissue disposition of urolithin A, an ellagitannin‐derived metabolite, in mice
Ellagitannins (ETs) are bioactive polyphenols present in some fruits (pomegranates, strawberries, red and black raspberries) and… 
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