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urolithin A

National Institutes of Health

Papers overview

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2019
2019
Urolithin A, a Gut Metabolite, Induces Metabolic Reprogramming of Adipose Tissue by Promoting M2 Macrophage Polarization and Mitochondrial Function (OR12-02-19).
Objectives Macrophage polarization into pro-inflammatory M1 status is associated with the pathologic progression of adipose… 
2019
2019
Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19)
Muscle health declines with aging and is accompanied by impairment of skeletal muscle mitochondrial function. Strategies… 
2018
2018
Ellagic Acid and Urolithin A Improve Insulin Sensitivity in Diet-Induced Insulin Resistant Mice and Reduce Detrimental Effects of Palmitate Administration in Differentiated C2C12 Myotubes.
Author(s): Chan, Brenda | Advisor(s): Clarke, Catherine F. | Abstract: Insulin resistance has been spreading as food and… 
2017
2017
but not iso-Urolithin A and Urolithin B , attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes 1
2017
2017
Abstract 5259: Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling
Pancreatic ductal adenocarcinoma (PDAC) is the 3rd leading cause of cancer-related mortality in the United States. Most patients… 
2016
2016
Fungal infection: Protecting from Candida albicans
2015
2015
Urolithin A, Walnut Polyphenol Metabolite, Causes Cell Cycle Arrest and Apoptosis in Prostate and Breast Cancer Cells
The identification of new agents that may modulate the progression of cancer cell growth is of great interest. In this regard… 
2011
2011
Urolithin A and Ellagic Acid Inhibit Prostate Cancer Through Different Molecular Mechanisms: Implications of Gut Microbiome Metabolism for Cancer Prevention
There is an increased interest in the production by the gut microbiome of metabolites of phytochemicals with chemorpreventive… 
2008
2008
Safety evaluation of an oak-flavored milk powder containing ellagitannins upon oral administration in the rat.
Ellagitannins are phenolic compounds that occur in a number of dietary sources such as walnuts, raspberries, pomegranate… 
2007
2007
Pharmacokinetics and tissue disposition of urolithin A, an ellagitannin‐derived metabolite, in mice
Ellagitannins (ETs) are bioactive polyphenols present in some fruits (pomegranates, strawberries, red and black raspberries) and… 
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