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uracil phosphoribosyltransferase activity

Known as: uridylate pyrophosphorylase activity, uridylic pyrophosphorylase activity, uridine monophosphate pyrophosphorylase activity 
Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil. [EC:2.4.2.9, RHEA:13020]
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Encapsulated follicular thyroid tumor with equivocal nuclear changes, so-called well-differentiated tumor of uncertain malignant potential: a morphological, immunohistochemical, and molecular…
There is a continuous debate regarding the classification of thyroid follicular lesions and the term "well-differentiated tumor… Expand
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2008
2008
Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase
Non-natural l-nucleoside analogues are increasingly used as therapeutic agents to treat cancer and viral infections. To be active… Expand
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Highly Cited
2006
Highly Cited
2006
The structure of a protein primer-polymerase complex in the initiation of genome replication.
Picornavirus RNA replication is initiated by the covalent attachment of a UMP molecule to the hydroxyl group of a tyrosine in the… Expand
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2006
2006
Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics.
Inhibitors of orotidine monophosphate decarboxylase (ODCase) have applications in RNA viral, parasitic, and other infectious… Expand
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2002
2002
Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates.
Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK);EC 2.7.4.14] plays a crucial role in the formation of UDP… Expand
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2001
2001
Effect of galactose and glucose on the exopolysaccharide production and the activities of biosynthetic enzymes in Lactobacillus casei CRL 87.
AIMS The objective of this work was to study the influence of the sugar source on exopolysaccharide (EPS) production and the… Expand
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2001
2001
Improved chemical synthesis of UDP-galactofuranose.
[reaction: see text] A reliable and efficient synthetic route to UDP-alpha-D-galactofuranose (UDP-Galf) has been developed… Expand
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1986
1986
ADPglucose Pyrophosphorylase Is Encoded by Different mRNA Transcripts in Leaf and Endosperm of Cereals.
Western blots of soluble protein from wheat, rice, and corn showed that ADPglucose pyrophosphorylase subunits have a size of 50… Expand
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1986
1986
On the role of cytidine deaminase in cellular metabolism.
  • P. Nygaard
  • Advances in experimental medicine and biology
  • 1986
    • Corpus ID: 42470524
Pyrimidine nucleotides are synthesized either denovo or via salvage pathways from preformed pyrimidine compounds. The denovo… Expand
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1980
1980
Multiple forms of maize endosperm adp-glucose pyrophosphorylase and their control by shrunken-2 and brittle-2.
Heat-labile and heat stable forms of ADP-glucose pyrophosphorylase were identified in the maize endosperm. The heat-labile form… Expand
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