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uracil phosphoribosyltransferase activity

Known as: uridylate pyrophosphorylase activity, uridylic pyrophosphorylase activity, uridine monophosphate pyrophosphorylase activity 
Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil. [EC:2.4.2.9, RHEA:13020]
National Institutes of Health

Papers overview

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2006
2006
Design of inhibitors of orotidine monophosphate decarboxylase using bioisosteric replacement and determination of inhibition kinetics.
Inhibitors of orotidine monophosphate decarboxylase (ODCase) have applications in RNA viral, parasitic, and other infectious… 
2004
2004
Zur Wirkung von 2,5-Dimethoxy-äthoxy-3,6-bis-äthyleniminobenzochinon-1,4 (BAYER A 139) auf die Glykolyse von Ascites-Tumorzellen
Nach Einwirkung der carcinostatischen Äthyleniminchinon-Verbindung A 139 auf glykolysierende Ascites-Tumorzellen sinkt der DPN… 
2001
2001
Lethality of glnD null mutations in Azotobacter vinelandii is suppressible by prevention of glutamine synthetase adenylylation.
GlnD is a pivotal protein in sensing intracellular levels of fixed nitrogen and has been best studied in enteric bacteria, where… 
1990
1990
Direct spectrophotometric assays for orotate phosphoribosyltransferase and orotidylate decarboxylase.
Highly Cited
1986
Highly Cited
1986
ADPglucose Pyrophosphorylase Is Encoded by Different mRNA Transcripts in Leaf and Endosperm of Cereals.
Western blots of soluble protein from wheat, rice, and corn showed that ADPglucose pyrophosphorylase subunits have a size of 50… 
1984
1984
Decreased activity of UMP pyrophosphorylase associated with resistance to 5-fluorocytosine in Candida albicans
UMP pyrophosphorylase activity was assayed in crude lysates prepared from Candida albicans. Specific activity of UMP… 
1983
1983
Mechanism of action of 2',5-difluoro-1-arabinosyluracil.
Results are described which demonstrate that the cytotoxic action of 2',5-difluoro-1-arabinosyluracil (FFara-Ura) involves… 
1979
1979
Activities of DNA polymerases and RNA polymerases detected in situ in growing and differentiating cells of root cortex
SummaryActivities of DNA polymerases and RNA polymerases were studied by autoradiographic methods in growing and differentiating… 
1969
1969
Hereditary orotic aciduria with normal growth and development.
Hereditary orotic aciduria was found in a 7-year-old girl who had anemia, leukopenia, a megaloblastic bone marrow, crystalluria… 
1966
1966
Studies on 5-aminouridine.
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