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undecaprenyl pyrophosphate synthetase

Known as: di-trans, poly-cis-decaprenylcistransferase, undecaprenyl PP synthetase, undecaprenyl diphosphate synthase 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
cis-Prenyltransferases (cis-PTs) constitute a large family of enzymes conserved during evolution and present in all domains of… 
2016
2016
We synthesized potential inhibitors of farnesyl diphosphate synthase (FPPS), undecaprenyl diphosphate synthase (UPPS), or… 
2015
2015
We report the results of an investigation of the activity of a series of amidine and bisamidine compounds against Staphylococcus… 
2015
2015
With the rise in antibiotic resistance, there is interest in discovering new drugs active against new targets. Here, we… 
2014
2014
There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin… 
Highly Cited
2007
Highly Cited
2007
Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS… 
Highly Cited
2001
Highly Cited
2001
Undecaprenyl diphosphate synthase (UPS) catalyzes the cis-prenyl chain elongation onto trans, trans-farnesyl diphosphate (FPP) to… 
Highly Cited
1982
Highly Cited
1982
Undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase were partially purified and characterized from…