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undecaprenyl pyrophosphate synthetase

Known as: di-trans, poly-cis-decaprenylcistransferase, undecaprenyl PP synthetase, undecaprenyl diphosphate synthase 
 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
cis-Prenyltransferases (cis-PTs) constitute a large family of enzymes conserved during evolution and present in all domains of… Expand
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2016
2016
We synthesized potential inhibitors of farnesyl diphosphate synthase (FPPS), undecaprenyl diphosphate synthase (UPPS), or… Expand
2015
2015
  • W. Zhu, Yang Wang, +7 authors E. Oldfield
  • Journal of medicinal chemistry
  • 2015
  • Corpus ID: 207234296
We report the results of an investigation of the activity of a series of amidine and bisamidine compounds against Staphylococcus… Expand
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2014
2014
There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin… Expand
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2012
2012
We report the discovery of antibacterial leads, keto- and diketo-acids, targeting two prenyl transferases: undecaprenyl… Expand
Highly Cited
2007
Highly Cited
2007
  • R. Guo, R. Cao, +11 authors A. Wang
  • Proceedings of the National Academy of Sciences
  • 2007
  • Corpus ID: 11243599
Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS… Expand
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Highly Cited
2001
Highly Cited
2001
Undecaprenyl diphosphate synthase (UPS) catalyzes the cis-prenyl chain elongation onto trans, trans-farnesyl diphosphate (FPP) to… Expand
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Highly Cited
1982
Highly Cited
1982
Undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase were partially purified and characterized from… Expand
1980
1980
Abstract Three prenyl transferases in Micrococcus luteus were recovered in the soluble fraction following cell disruption… Expand
1974
1974
Abstract A soluble long-chain polyprenyl pyrophosphate synthetase has been isolated from Lactobacillus plantarum and partially… Expand