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undecaprenyl pyrophosphate synthetase

Known as: di-trans, poly-cis-decaprenylcistransferase, undecaprenyl PP synthetase, undecaprenyl diphosphate synthase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2015
012319822015

Papers overview

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2016
2016
Structure and Function of a "Head-to-Middle" Prenyltransferase: Lavandulyl Diphosphate Synthase.
We report the first X-ray structure of the unique "head-to-middle" monoterpene synthase, lavandulyl diphosphate synthase (LPPS… (More)
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2015
2015
Antibacterial drug leads: DNA and enzyme multitargeting.
We report the results of an investigation of the activity of a series of amidine and bisamidine compounds against Staphylococcus… (More)
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2015
2015
A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery.
With the rise in antibiotic resistance, there is interest in discovering new drugs active against new targets. Here, we… (More)
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2015
2015
Phenotypic and transcriptional analysis appear that bacterial cell wall assembly stop by conserved inner membrane protein (ElyC) gene disruption stimulates the enterobacterial common antigen (ECA…
This study investigated the involvement of Conserved inner membrane protein (YcbC) in the regulation of Enterobacterial Common… (More)
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Review
2012
Review
2012
Undecaprenyl diphosphate synthase, a cis-prenyltransferase synthesizing lipid carrier for bacterial cell wall biosynthesis.
A group of prenyltransferases produce linear lipids by catalyzing consecutive condensation reactions of farnesyl diphosphate (FPP… (More)
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Review
2012
Review
2012
Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis.
Isoprenoids are an intensive group of compounds made from isopentenyl diphosphate (IPP), catalyzed by prenyltransferases such as… (More)
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2007
2007
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Bisphosphonate drugs (e.g., Fosamax and Zometa) are thought to act primarily by inhibiting farnesyl diphosphate synthase (FPPS… (More)
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1982
1982
Prenyltransferases of Bacillus subtilis: undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase.
Undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase were partially purified and characterized from… (More)
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