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undecaprenyl pyrophosphate synthetase

Known as: di-trans, poly-cis-decaprenylcistransferase, undecaprenyl PP synthetase, undecaprenyl diphosphate synthase 
National Institutes of Health

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uppS protein, E coli

Papers overview

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2016
2016
Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase
We synthesized a series of benzoic acids and phenylphosphonic acids and investigated their effects on the growth of… 
2015
2015
A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer‐aided Drug Discovery
With the rise in antibiotic resistance, there is interest in discovering new drugs active against new targets. Here, we… 
2014
2014
Molecular Docking study of Catechins compounds from Camellia sinensis against UPPS in Staphylococcus aureus
Antibiotics resistant Staphylococcus aureus ( S. aureus ) is an emerging concern in the medical field. Due to their increasing… 
2014
2014
Title Undecaprenyl diphosphate synthase inhibitors : Antibacterial drug leads Permalink
There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin… 
Review
2012
Review
2012
Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: a cis-prenyltransferase for bacterial peptidoglycan biosynthesis.
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