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tyrphostin AG 1024

Known as: AG 1024, AG-1024, AG1024 
National Institutes of Health

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Tyrphostins

Papers overview

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2014
2014
Radiation-induced accelerated senescence
Damage to normal tissue is a limiting factor for clinical radiation for cancer eradication. Ionizing radiation can induce a… 
2011
2011
Phosphorylated Insulin-Like Growth Factor 1 Receptor is Implicated in Resistance to the Cytostatic Effect of Gefitinib in Colorectal Cancer Cells
IntroductionThe ability of certain cancer cells to maintain signaling via the phosphoinositide-3-kinase/Akt and/or Ras/mitogen… 
2009
2009
Enhancement of AG1024-induced H9c2 cardiomyoblast cell apoptosis via the interaction of IGF2R with Galpha proteins and its downstream PKA and PLC-beta modulators by IGF-II.
Our previous studies found that insulin-like growth factor-I receptor (IGF1R) signaling blockade caused cardiac hypertrophy, and… 
2008
2008
Decoy Receptor 3 Expression in AsPC-1 Human Pancreatic Adenocarcinoma Cells via the Phosphatidylinositol 3-Kinase-, Akt-, and NF-κB-Dependent Pathway1
Many cancers develop different means of escaping destruction by the immune system, such as resistance to Fas ligand (FasL)-Fas… 
2008
2008
Insulin-like growth factor-1 attenuates cisplatin-induced gammaH2AX formation and DNA double-strand breaks repair pathway in non-small cell lung cancer.
2007
2007
Comparison of three approaches for inhibiting insulin-like growth factor I receptor and their effects on NSCLC cell lines in vitro
The insulin-like growth factor-1 receptor (IGF-1R) mitogenic signaling mediates malignant cell survival by many complex and… 
2006
2006
The relationship between the insulin-like growth factor-1 system and the oestrogen metabolising enzymes in breast cancer tissue and its adjacent non-cancerous tissue
AimsPrevious studies have shown that oestrogen and Insulin-like Growth Factor-1 (IGF-1) act synergistically and cross-stimulatory… 
2005
2005
IGF-I-induced enhancement of contractile response in organ-cultured aortae from diabetic rats is mediated by sustained thromboxane A2 release from endothelial cells.
We have investigated the mechanisms underlying the changes in vascular contractile responsiveness induced by insulin and IGF-I in… 
2004
2004
The involvement of platelet-derived growth factor receptors and insulin-like growth factor-I receptors signaling during mineralized nodule formation by human periodontal ligament cells.
BACKGROUND AND OBJECTIVE Periodontal ligament cells are regarded to have the capacity to differentiate into cementoblasts or… 
1999
1999
A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression.
A highly sensitive method for determination of insulin receptor (IR) kinase activity in whole cells, which is based on a STAT5… 
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