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tumor infiltrating lymphocyte therapy

Known as: TIL, therapy, tumor infiltrating lymphocyte 
A form of adoptive cell transfer in which lymphocytes are isolated from a patient's tumor, grown in vitro, and then infused into the patient in… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Immunotherapy
Lymphocytes, Tumor-Infiltrating

Papers overview

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Highly Cited
2014
Highly Cited
2014
Unleashing the immune system: PD-1 and PD-Ls in the pre-treatment tumor microenvironment and correlation with response to PD-1/PD-L1 blockade
Focal tumor cell PD-L1 expression adjacent to TIL can be used as a surrogate marker of an ongoing antitumor host response, which… 
Review
2014
Review
2014
At the Bedside: Adoptive cell therapy for melanoma—clinical development
Adoptive cell therapy for melanoma, particularly using TIL, consists of a complex and difficult set of procedures, although it… 
2014
2014
Triple‐incision laparoscopic distal gastrectomy for the resection of gastric cancer: Comparison with conventional laparoscopy‐assisted distal gastrectomy
Reduced port surgery and single‐port surgery are currently in the spotlight as next‐generation, minimally invasive surgical… 
2007
2007
Identification of DR9-restricted XAGE antigen on lung adenocarcinoma recognized by autologous CD4 T-cells.
We previously demonstrated a dominant IgG response against XAGE-1b antigen in a lung cancer patient by serological analysis of… 
Highly Cited
1997
Highly Cited
1997
Interleukin‐7 (IL‐7) in Colorectal Cancer: IL‐7 is Produced by Tissues from Colorectal Cancer and Promotes Preferential Expansion of Tumour Infiltrating Lymphocytes
Despite increasing survival rates for patients with colorectal cancer, additional treatment options are required, including… 
1997
1997
T-cell receptor repertoire in matched MART-1 peptide-stimulated peripheral blood lymphocytes and tumor-infiltrating lymphocytes.
Characterization of tumor-associated antigens (TAAs) recognized by CTLs makes the consideration of therapeutic strategies based… 
1994
1994
T‐Cell Receptor Repertoire in Tumor‐Infiltrating Lymphocytes. Analysis of Melanoma‐Specific Long‐Term Lines
Cytotoxic T-lymphocytes (CTLs) can be isolated from human melanoma biopsies that specifically lyse autologous melanoma in vitro… 
1992
1992
Phenotypic and functional characterization of cytotoxic cells derived from endomyocardial biopsies in human cardiac allografts.
1990
1990
Til from renal‐cell carcinoma: Restimulation with tumor influences proliferation and cytolytic activity
TIL were cultured from human renal‐cell carcinoma (RCC) in 1,000 U/ml rIL2 and restimulated with autologous tumor in efforts to… 
1989
1989
Properties of recombinant interleukin 2‐cultured tumor‐infiltrating lymphocytes in human lung cancer
It is thought that TIL can be activated in vitro by rIL‐2 and acquire specific anti‐tumor activity. In this study, we… 
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