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tubulazole

Known as: ethyl (4-(2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethylthio)phenyl)carbamate, tubulozole 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antineoplastic AgentsAntiprotozoal AgentsDioxolanes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation.
2004
2004
Effects of microtubule inhibitors on protein synthesis inPlasmodium falciparum
At low concentrations, both isomers of tubulozole (C, T) inhibitPlasmodium falciparum but only tubulozole C inhibits mammalian… 
2003
2003
The effect of the microtubule inhibitor tubulozole-C on the tegument of triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica
The benzimidazole derivative, triclabendazole is the main drug used against Fasciola hepatica, although its precise mode of… 
Highly Cited
2001
Highly Cited
2001
The in vivo gut micronucleus test detects clastogens and aneugens given by gavage.
A general testing battery for pharmaceuticals includes a bacterial gene mutation assay, an in vitro chromosomal aberration or a… 
1995
1995
The effect of triclabendazole ("Fasinex") on protein synthesis by the liver fluke, Fasciola hepatica.
1993
1993
Cytoskeletal agents inhibit motility and adherence of human tumor cells.
Cytoskeletal agents have been demonstrated to inhibit stimulated motility and substrate adherence by the human tumor cell line… 
1993
1993
Fasciola hepatica: the effect of the microtubule inhibitors colchicine and tubulozole-C on the ultrastructure of the adult fluke
Summary The effect of the microtubule inhibitors coichicine (1×10−3 M) and tubulozole-C(1×10−6 M) on the ultrastructure of adult… 
1990
1990
Mode of action of tubulozoles against Plasmodium falciparum in vitro
The mode of action of the tubulozole isomers, recently recognized as a new class of potential antimalarial agents, was… 
1985
1985
Effects of tubulozole on the microtubule system of cells in culture and in vivo.
Light and electron microscopic investigations on mammalian cells in vitro and in vivo showed that tubulozole-C (R 46 846), the… 
1985
1985
The Kidney Invasion Test: an assay allowing macroscopic quantification of malignant invasion in vivo. Comparison between the microtubule inhibitor tubulozole and the podophyllotoxin congener…
When MO4 tumor fragments were implanted under the renal capsule of syngeneic or allogeneic mice, invasion of the renal parenchyma… 
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