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tubulazole

Known as: ethyl (4-(2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-ylmethylthio)phenyl)carbamate, tubulozole 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antineoplastic AgentsAntiprotozoal AgentsDioxolanes

Papers overview

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2004
2004
Effects of microtubule inhibitors on protein synthesis inPlasmodium falciparum
At low concentrations, both isomers of tubulozole (C, T) inhibitPlasmodium falciparum but only tubulozole C inhibits mammalian… 
2003
2003
The effect of the microtubule inhibitor tubulozole-C on the tegument of triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica
The benzimidazole derivative, triclabendazole is the main drug used against Fasciola hepatica, although its precise mode of… 
1991
1991
Characterization of muscarinic receptors of bovine adrenal chromaffin cells: binding, secretion and anti-microtubule drug effects.
1991
1991
Role of cytoskeleton in isotonic cell volume control of rabbit proximal tubules.
Stability of mammalian cell volume depends primarily on the sodium pump. When active cation transport of rabbit renal proximal… 
1990
1990
Mode of action of tubulozoles against Plasmodium falciparum in vitro
The mode of action of the tubulozole isomers, recently recognized as a new class of potential antimalarial agents, was… 
1989
1989
Microtubules and actin microfilaments in the amphibian bladder granular cells
Microtubules and microfilaments were localized by an immunocytochemical method in the granular cells of the frog bladder after… 
1987
1987
Effect of tubulozole, a new synthetic microtubule inhibitor, on the induction of casein gene expression by prolactin
Colchicine and related drugs are known to inhibit milk secretion. They are also able to prevent stimulation of casein and DNA… 
1986
1986
Tubulozole: A New Stereoselective Microtubule Inhibitor a
1985
1985
Effects of tubulozole on the microtubule system of cells in culture and in vivo.
Light and electron microscopic investigations on mammalian cells in vitro and in vivo showed that tubulozole-C (R 46 846), the… 
1985
1985
The Kidney Invasion Test: an assay allowing macroscopic quantification of malignant invasion in vivo. Comparison between the microtubule inhibitor tubulozole and the podophyllotoxin congener…
When MO4 tumor fragments were implanted under the renal capsule of syngeneic or allogeneic mice, invasion of the renal parenchyma… 
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