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tryparsamide

Known as: sodium (4-(carbamoylmethylamino)phenyl)methyl-oxido-arsinic acid 
An arsenic compound with activity against Spirochaetes bacteria. Tryparsamide is used in the treatment of syphilis and African sleeping sickness.
National Institutes of Health

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Arsenicals

Papers overview

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1980
1980
Trypanosoma rhodesiense: semiautomated microtesting for quantitation of antitrypanosomal activity in vitro.
1966
1966
Analysis of the development of arsenical resistance in trypanosomes in vitro.
1957
1957
Melarsen in the treatment of Trypanosoma gambiense infection in man.
1951
1951
The efficacy of certain trypanocidal compounds against Trypanosoma gambiense infection in man.
1948
1948
Sleeping sickness of an unusual type in Sierra Leone and its attempted control.
Review
1948
Review
1948
The control of sleeping sickness in Nigeria.
1938
1938
Nitritoid Reaction following an Injection of Tryparsamide.
Consulting the literature on nitritoid reactions, we found only 2 bona fide cases of reaction occurring after the use of… 
Review
1937
Review
1937
TRYPARSAMIDE THERAPY OF NEUROSYPHILIS AND ATROPHY OF THE OPTIC NERVE
It has been fifteen years since the first injection of tryparsamide was given for syphilis of the central nervous system. 1 The… 
1936
1936
DERMATITIS DUE TO TRYPARSAMIDE: REPORT OF A CASE
Dermatitis due to tryparsamide is rare. Ebaugh and Dickson 1 Skoog, 2 O'Leary and Becker, 3 Phelps 4 and Bragman 5 recorded a… 
1932
1932
THE EFFECT OF ARSENIC ON RABBITS: MICROCHEMICAL STUDIES FOLLOWING THE ADMINISTRATION OF THE ARSPHENAMINES AND TRYPARSAMIDE
Since the introduction of arsphenamine and neoarsphenamine by Ehrlich, information regarding the causes of accidents following… 
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