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tripterine

Known as: 3-hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic acid, celastrol 
National Institutes of Health

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Broader (1)

Triterpenes

Papers overview

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2017
2017
Investigation of the influence of glycyrrhizin on the pharmacokinetics of celastrol in rats using LC-MS and its potential mechanism
Abstract 1. The aim of this study was to investigate the effects of glycyrrhizin on the pharmacokinetics of celastrol in rats. 2… 
2015
2015
Celastrol blocks binding of lipopolysaccharides to a Toll-like receptor4/myeloid differentiation factor2 complex in a thiol-dependent manner.
Highly Cited
2014
Highly Cited
2014
The Systemic Amyloid Precursor Transthyretin (TTR) Behaves as a Neuronal Stress Protein Regulated by HSF1 in SH-SY5Y Human Neuroblastoma Cells and APP23 Alzheimer's Disease Model Mice
Increased neuronal synthesis of transthyretin (TTR) may favorably impact on Alzheimer's disease (AD) because TTR has been shown… 
2013
2013
Anti-invasive effects of celastrol in hypoxia-induced fibroblast-like synoviocyte through suppressing of HIF-1α/CXCR4 signaling pathway.
2012
2012
Induction of heat shock proteins in cerebral cortical cultures by celastrol
Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS) are ‘protein misfolding disorders’ of the mature… 
2010
2010
Pharmacogenomic Approach Reveals a Role for the xc− Cystine/Glutamate Antiporter in Growth and Celastrol Resistance of Glioma Cell Lines
The xc− cystine/glutamate antiporter has been implicated in GSH-based chemoresistance because it mediates cellular uptake of… 
2008
2008
Calpain‐mediated androgen receptor breakdown in apoptotic prostate cancer cells
Since androgen receptor (AR) plays an important role in prostate cancer development and progression, androgen‐ablation has been… 
2002
2002
Quantitative determination for cytotoxic Friedo-nor-oleanane derivatives from five morphological types of Maytenus ilicifolia (Celastraceae) by reverse-phase high-performance liquid chromatography.
Five different morphological types of Maytenus ilicifolia of the same age and harvested under the same conditions showed distinct… 
1998
1998
Novel cytokine release inhibitors. Part I: Triterpenes.
1980
1980
The cathedulin alkaloids.
Studies on fresh and dried leaf and shoot material of Catha edulis (khat) collected in Ethiopia, Kenya and the Yemen Arab… 
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