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tripchlorolide

Known as: tryptolide-12,13-chlorohydrin, Bisoxireno(4b,5:8a,9)phenanthro(1,2-c)furan-4(2H)-one, 11-chloro-1b,3,6,6b,7,7a,9,10,11,11a-decahydro-9,10-dihydroxy-1b-methyl-10-(1-methylethyl)-, (1bS-(1aR*,1balpha,6bbeta,7abeta,8aR*,9alpha,10beta,11alpha,11abeta))-, TW397 
National Institutes of Health

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2 relations

Broader (2)

DiterpenesPhenanthrenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
[Advances in the study of immunopharmacological effects and mechanisms of extracts of Tripterygium wilfordii Hook. f. in neuroimmunologic disorders].
Extracts of Chinese herb Tripterygium wilfordii Hook. f. (TWHF) have been found to have potent anti-inflammatory and… 
2007
2007
Simple method for determination of five terpenoids from different parts of Tripterygium wilfordii and its preparations by HPLC coupled with evaporative light scattering detection.
By optimizing the extraction, separation, and analytical conditions, a reliable and accurate high-performance liquid… 
2006
2006
A novel method to convert triptolide into tripchlorolide in Tripterygium wilfordii.
A new method has been established to convert triptolide (1) into tripchlorolide (2) directly in the Chinese herbal drug… 
2005
2005
Differential regulation of survivin by p53 contributes to cell cycle dependent apoptosis
ABSTRACTRecent studies indicate that cell-cycle checkpoints are tightly correlated with the regulation of apoptosis, in which p53… 
Highly Cited
2003
Highly Cited
2003
Neurotrophic and Neuroprotective Effects of Tripchlorolide, an Extract of Chinese Herb Tripterygium wilfordii Hook F, on Dopaminergic Neurons
It has been reported recently that the immunosuppressant FK506 produced neurotrophic and neuroprotective effects on dopaminergic… 
1999
1999
Effects of tripchlorolide on the epididymides and testes of rats.
AIM To further evaluate the antifertility effects of tripchlorolide, a derivative of triptolide produced at the extraction… 
1996
1996
Tripchlorolide inhibition of Ca~(2+) influx in human ejaculated sperm, but not affecting contraction reaction of aorta and vas deferens in rats
Tripchlorolide (T4), an active monomer isolated from Chinese herb Tripterygium wilfordii, could enhance not only antiinflammatory… 
1994
1994
Effects of tripchlorolide (T4) of Tripterygium wilfordii hook on the production of prostaglandin E2 by synovial cells of rheumatoid arthritis
The effects of tripchlorolide, an active ingredient (T4) of Tripterygium wilfordii Hook on the production of prostaglandin E2… 
1993
1993
[Studies on diterpenoids from leaves of Tripterygium wilfordii].
Tripterygium wilfordii Hook f. has been used as a medicinal herb in traditional Chinese medicine and as an insecticide by the… 
1992
1992
[Structure modification of triptolide, a diterpenoid from Tripterygium wilfordii].
In this paper, the structure modification of triptolide was studied and nine trip tolide derivatives were synthesized. A… 
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