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triheptanoin

Known as: glyceroltriheptanoate, glyceryl triheptanoate 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Triglycerides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease primarily characterized by loss of motor neurons in… Expand
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2016
2016
Triheptanoin treatment in patients with pediatric cardiomyopathy associated with long chain-fatty acid oxidation disorders.
Long-chain fatty acid oxidation disorders (LC-FAOD) can cause cardiac hypertrophy and cardiomyopathy, often presenting in infancy… Expand
Highly Cited
2015
Highly Cited
2015
Triheptanoin dramatically reduces paroxysmal motor disorder in patients with GLUT1 deficiency
Objective On the basis of our previous work with triheptanoin, which provides key substrates to the Krebs cycle in the brain, we… Expand
Highly Cited
2015
Highly Cited
2015
Triheptanoin improves brain energy metabolism in patients with Huntington disease
Objective: Based on our previous work in Huntington disease (HD) showing improved energy metabolism in muscle by providing… Expand
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2014
2014
Anaplerotic Triheptanoin Diet Enhances Mitochondrial Substrate Use to Remodel the Metabolome and Improve Lifespan, Motor Function, and Sociability in MeCP2-Null Mice
Rett syndrome (RTT) is an autism spectrum disorder (ASD) caused by mutations in the X-linked MECP2 gene that encodes methyl-CpG… Expand
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Highly Cited
2014
Highly Cited
2014
Triheptanoin for glucose transporter type I deficiency (G1D): modulation of human ictogenesis, cerebral metabolic rate, and cognitive indices by a food supplement.
IMPORTANCE Disorders of brain metabolism are multiform in their mechanisms and manifestations, many of which remain… Expand
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Highly Cited
2010
Highly Cited
2010
Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models
We hypothesized that in epileptic brains citric acid cycle intermediate levels may be deficient leading to hyperexcitability… Expand
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Highly Cited
2006
Highly Cited
2006
Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats.
A new chronic treatment for inherited disorders of long-chain fatty acid oxidation involves administering up to one-third of… Expand
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Highly Cited
2005
Highly Cited
2005
Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin.
Ghrelin, an acylated brain and gut peptide, is primarily produced by endocrine cells of the gastric mucosa for secretion into the… Expand
Highly Cited
2002
Highly Cited
2002
Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride.
The current dietary treatment of long-chain fatty acid oxidation defects (high carbohydrate with medium-even-chain triglycerides… Expand
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