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triflusal
Known as:
2- (acetyloxy)-4-(trifluoromethyl)benzoic acid
, 2-acetoxy-4-trifluoromethylbenzoic acid
National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
Disgren
Broader (2)
Platelet Aggregation Inhibitors
Salicylates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Letter by Borja and Garcia-Rafanell regarding article, "Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the…
J. Borja
,
J. García-Rafanell
Stroke
2011
Corpus ID: 2523561
To the Editor: In “Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack,”1 the authors…
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Review
2009
Review
2009
Triflusal: an old drug in modern antiplatelet therapy. Review of its action, use, safety and effectiveness.
H. Anninos
,
G. Andrikopoulos
,
Socrates Pastromas
,
D. Sakellariou
,
G. Theodorakis
,
P. Vardas
Hellenic Journal of Cardiology
2009
Corpus ID: 25036149
D espite preventive measures and improved long-term prognosis, the prevalence of cardiovascular diseases in the majority of the…
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2004
2004
Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation
F. Pérez-Gómez
,
E. Alegrı́a
,
J. Berjón
2004
Corpus ID: 81912245
2002
2002
Decrease of Proinflammatory Molecules Correlates With Neuroprotective Effect of the Fluorinated Salicylate Triflusal After Postnatal Excitotoxic Damage
L. Acarín
,
B. González
,
B. Castellano
Stroke
2002
Corpus ID: 2467830
Background and Purpose— The fluorinated salicylate triflusal has been shown to have a neuroprotective effect after an excitotoxic…
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2001
2001
Triflusal Posttreatment Inhibits Glial Nuclear Factor-&khgr;B, Downregulates the Glial Response, and Is Neuroprotective in an Excitotoxic Injury Model in Postnatal Brain
L. Acarín
,
B. González
,
B. Castellano
Stroke
2001
Corpus ID: 23110266
Background and Purpose— Nuclear factor-&khgr;B (NF-&khgr;B) and the signal transducer and activator of transcription 3 (STAT3…
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Highly Cited
1999
Highly Cited
1999
Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid.
A. D. Arriba
,
F. Cavalcanti
,
+5 authors
J. Forn
Molecular Pharmacology
1999
Corpus ID: 6453900
The therapeutic potential of drugs that block the induction of cyclooxygenase-2 has been emphasized. When two 4-trifluoromethyl…
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1991
1991
Pharmacokinetics of triflusal and its main metabolite HTB in healthy subjects following a single oral dose
J. Ramis
,
R. Mis
,
J. Forn
,
J. Torrent
,
E. Gorina
,
F. Jané
European journal of drug metabolism and…
1991
Corpus ID: 6287466
SummaryThe pharmacokinetic profile of triflusal (2-acetoxy-4-trifluoromethyl benzoic acid) and its main metabolite HTB (2-hydroxy…
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1990
1990
Pharmacokinetics of triflusal after single and repeated doses in man.
J. Ramis
,
J. Torrent
,
+4 authors
Javier Forn
International journal of clinical pharmacology…
1990
Corpus ID: 42256376
Triflusal pharmacokinetics were evaluated in 8 healthy subjects after a single 300 mg dose and after repeated doses of 300 mg…
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1986
1986
Effect of triflusal and other salicylic acid derivatives on cyclic AMP levels in rat platelets.
J. García-Rafanell
,
J. Ramis
,
L. Gómez
,
J. Forn
Archives internationales de pharmacodynamie et de…
1986
Corpus ID: 30241686
The effect of triflusal, acetylsalicylic acid (ASA), and of their principal metabolites 2-hydroxy-4-trifluoromethylbenzoic acid…
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1985
1985
Effects of triflusal in patients with prosthetic heart valves.
M. Domínguez
,
M. Vacas
,
+4 authors
J. Forn
Clinical Therapeutics
1985
Corpus ID: 30341934
The biological effects of a new antiplatelet agent, triflusal, were evaluated in patients with cardiac valvular prostheses. Each…
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