triazene

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Triazene compounds of clinical interest (i.e. dacarbazine and temozolomide) are a group of alkylating agents with similar… (More)
Is this relevant?
2004
2004
We have previously reported the synthesis of SMA41, a unimolecular combination of an epidermal growth factor receptor (EGFR… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
2002
2002
Abstract Purpose. Previous studies have demonstrated enhanced potency associated with the binary [DNA/epidermal growth factor… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
1999
1999
Methylating triazenes have shown marked antileukemic effects, possibly through generation of a variety of DNA adducts. Cells… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Postreplicative mismatch repair plays a major role in mediating the cytotoxicity of agents generating O6-methylguanine in DNA. We… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
1995
1995
BACKGROUND A clinical pilot study performed by our group showed that dacarbazine can induce a marked reduction of blast cells in… (More)
Is this relevant?
1995
1995
Previous studies demonstrated that triazene compounds (TZC) possess antitumor, antimetastatic and immunosuppressive activity, and… (More)
Is this relevant?
1995
1995
High levels of O6-alkylguanine-DNA-alkyltransferase (OGAT) can, at least in part, account for tumor cell resistance to O6… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
A number of 3-alkyl analogues of the experimental antitumor drug mitozolomide [8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Interaction of 5-diazoimidazole-4-carboxamide and alkyl and aryl isocyanates in the dark affords 8-carbamoyl-3-substituted… (More)
Is this relevant?