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tretinoin liposome

Known as: Tretinoin Liposomal, Liposomal all-trans-retinoic acid, TretinoinLF 
An intravenous formulation of tretinoin (vitamin A acid or all-trans retinoic acid) encased in liposomes. Tretinoin is a naturally occurring retinoic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Frequently occurring skin irritancy and flare-up reactions impede the use of topical tretinoin for acne vulgaris due to poor… Expand
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2004
2004
SummaryBecause of their antiproliferative and differentiation-inducing properties, retinoids have been used clinically as… Expand
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Highly Cited
2003
Highly Cited
2003
PURPOSE To determine single-and multiple-dose pharmacokinetics of liposomal-all- trans -retinoic acid (Atragen) following… Expand
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2002
2002
We previously developed a murine model of acute promyelocytic leukemia (APL) by using human cathepsin G gene regulatory elements… Expand
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2002
2002
A multicenter trial was conducted to determine the efficacy and toxicity of escalating dosages of liposomal tretinoin (all‐trans… Expand
Highly Cited
2000
Highly Cited
2000
An attempt was made to pharmaceutically develop a topical liposomal tretinoin (TRE) gel and clinically evaluate the developed… Expand
1997
1997
Retinoids have been shown to modulate cell growth and differentiation in a variety of human tumor cell types, but their effects… Expand
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1997
1997
The topical application of tretinoin is a well-established approach to the treatment of acne vulgaris. However, induced… Expand
Highly Cited
1996
Highly Cited
1996
We administered liposome-encapsulated all-trans retinoic acid (L-ATRA) to 48 patients with refractory hematologic malignancies… Expand
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Highly Cited
1993
Highly Cited
1993
All-trans-retinoic acid (ATRA) induces complete remissions in the majority of patients with acute promyelocytic leukemia. Despite… Expand
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