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translesion synthesis

Known as: bypass DNA synthesis 
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a… 
National Institutes of Health

Papers overview

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2015
2015
Somatic Mutations in Catalytic Core of POLK Reported in Prostate Cancer Alter Translesion DNA Synthesis
DNA polymerase kappa is a Y‐family polymerase that participates to bypass the damaged DNA known as translesion synthesis (TLS… 
Review
2006
Review
2006
Homology modeling of four Y-family, lesion-bypass DNA polymerases: the case that E. coli Pol IV and human Pol kappa are orthologs, and E. coli Pol V and human Pol eta are orthologs.
2005
2005
UBE2V2 (MMS2) is not required for effective immunoglobulin gene conversion or DNA damage tolerance in DT40.
2005
2005
The effect of the 2-amino group of 7,8-dihydro-8-oxo-2′-deoxyguanosine on translesion synthesis and duplex stability
Replication of DNA containing 7,8-dihydro-8-oxo-2′-deoxyguanosine (OxodG) gives rise to G → T transversions. The syn-isomer of… 
2003
2003
Translesion replication in cisplatin-treated xeroderma pigmentosum variant cells is also caffeine-sensitive: features of the error-prone DNA polymerase(s) involved in UV-mutagenesis.
2003
2003
Chemical rearrangement and repair pathways of 1,N6-ethenoadenine.
Highly Cited
2002
Highly Cited
2002
Genetics of mutagenesis in E. coli: various combinations of translesion polymerases (Pol II, IV and V) deal with lesion/sequence context diversity.
Review
2000
Review
2000
Lesions in DNA: hurdles for polymerases.
1995
1995
Frequency and Fidelity of Translesion Synthesis of Site-specific N-2-Acetylaminofluorene Adducts during DNA Replication in a Human Cell Extract (*)
We have previously analyzed the effects of site-specific N-2-acetylaminofluorene (AAF) adducts on the efficiency and frameshift… 
1989
1989
Translesion synthesis is the main component of SOS repair in bacteriophage lambda DNA
Agents that interfere with DNA replication in Escherichia coli induce physiological adaptations that increase the probability of… 
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