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translesion synthesis

Known as: bypass DNA synthesis 
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Translesion DNA synthesis and mutagenesis in prokaryotes.
The presence of unrepaired lesions in DNA represents a challenge for replication. Most, but not all, DNA lesions block the… 
Review
2009
Review
2009
Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.
Review
2008
Review
2008
PCNA modifications for regulation of post-replication repair pathways.
Review
2007
Review
2007
Y-family DNA polymerases in Escherichia coli.
Highly Cited
2006
Highly Cited
2006
Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations
Eukaryotic cells possess several mechanisms to protect the integrity of their DNA against damage. These include cell-cycle… 
Highly Cited
2004
Highly Cited
2004
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein.
Review
2003
Review
2003
The interacting pathways for prevention and repair of oxidative DNA damage.
Highly Cited
2003
Highly Cited
2003
Checkpoint activation regulates mutagenic translesion synthesis.
Cells have evolved checkpoint responses to arrest or delay the cell cycle, activate DNA repair networks, or induce apoptosis… 
Highly Cited
1991
Highly Cited
1991
The thymine-thymine pyrimidine-pyrimidone(6-4) ultraviolet light photoproduct is highly mutagenic and specifically induces 3' thymine-to-cytosine transitions in Escherichia coli.
We have constructed single-stranded, M13-based vectors that contain a specifically located thymine-thymine pyrimidine-pyrimidone… 
Highly Cited
1985
Highly Cited
1985
Mutagenic repair in Escherichia coli: products of the recA gene and of the umuD and umuC genes act at different steps in UV-induced mutagenesis.
When excision-deficient Escherichia coli carrying umuC or umuD alleles were exposed to visible light several hours after… 
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