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tonabersat

Known as: 6-acetyl-4-(3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo(b)pyran-3-ol, N-((3S,4S)-6-Acetyl-3-hydroxy-2,2-dimethylchroman-4-yl)-3-chloro-4-fluorobenzamide 
National Institutes of Health

Papers overview

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2017
2017
The cis benzopyran compound tonabersat (SB-220453) has previously been reported to inhibit connexin26 expression in the brain by… 
Review
2014
Review
2014
BACKGROUND Randomized clinical trials assessing the efficacy and tolerability of tonabersat compared with placebo as prophylaxis… 
Highly Cited
2009
Highly Cited
2009
Tonabersat is a novel putative migraine prophylactic agent with an unique stereospecific binding site in the brain. Tonabersat… 
Highly Cited
2009
Highly Cited
2009
Background.— Sensitization and activation of trigeminal neurons are implicated in the underlying pathology of migraine, acute… 
Highly Cited
2009
Highly Cited
2009
Tonabersat is a novel benzopyran derivative that blocks the cortical spreading depression proposed to be associated with migraine… 
2009
2009
The ability of tonabersat to relieve the symptoms of migraine attacks with or without aura was evaluated in a randomized, double… 
2001
2001
Spreading cortical depolarization and depression of electroencephalographic activity (SD) may underlie the aura and spreading… 
2001
2001
The effects of tonabersat (SB‐220453) were evaluated on trigeminal nerve ganglion stimulation‐induced sensory‐autonomic…