Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 209,922,989 papers from all fields of science
Search
Sign In
Create Free Account
tonabersat
Known as:
6-acetyl-4-(3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo(b)pyran-3-ol
, N-((3S,4S)-6-Acetyl-3-hydroxy-2,2-dimethylchroman-4-yl)-3-chloro-4-fluorobenzamide
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
3 relations
Broader (2)
Benzamides
Benzopyrans
Narrower (1)
SB 220453
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels
Yeri Kim
,
J. Griffin
,
+8 authors
C. Green
Neurotherapeutics
2017
Corpus ID: 22893443
The cis benzopyran compound tonabersat (SB-220453) has previously been reported to inhibit connexin26 expression in the brain by…
Expand
Review
2014
Review
2014
Tonabersat for migraine prophylaxis: a systematic review.
Yue Cao
,
Ou Jin Zheng
Pain Physician
2014
Corpus ID: 12280587
BACKGROUND Randomized clinical trials assessing the efficacy and tolerability of tonabersat compared with placebo as prophylaxis…
Expand
Review
2009
Review
2009
Progress report on new antiepileptic drugs: A summary of the Ninth Eilat Conference (EILAT IX)
M. Bialer
,
S. Johannessen
,
R. Levy
,
E. Perucca
,
T. Tomson
,
H. White
Epilepsy Research
2009
Corpus ID: 12417047
Highly Cited
2009
Highly Cited
2009
Randomized, Double-Blind, Placebo-Controlled, Proof-of-Concept Study of the Cortical Spreading Depression Inhibiting Agent Tonabersat in Migraine Prophylaxis
P. Goadsby
,
M. Ferrari
,
A. Csányi
,
J. Olesen
,
J. Mills
Cephalalgia
2009
Corpus ID: 205586017
Tonabersat is a novel putative migraine prophylactic agent with an unique stereospecific binding site in the brain. Tonabersat…
Expand
Highly Cited
2009
Highly Cited
2009
Tonabersat Inhibits Trigeminal Ganglion Neuronal‐Satellite Glial Cell Signaling
S. Damodaram
,
Srikanth Thalakoti
,
S. E. Freeman
,
F. Garrett
,
P. Durham
Headache
2009
Corpus ID: 205682852
Background.— Sensitization and activation of trigeminal neurons are implicated in the underlying pathology of migraine, acute…
Expand
Highly Cited
2009
Highly Cited
2009
Tonabersat, a Gap-Junction Modulator: Efficacy and Safety in Two Randomized, Placebo-Controlled, Dose-Ranging Studies of Acute Migraineceph
S. Silberstein
,
J. Schoenen
,
+4 authors
R. A. Howard
Cephalalgia
2009
Corpus ID: 1861258
Tonabersat is a novel benzopyran derivative that blocks the cortical spreading depression proposed to be associated with migraine…
Expand
Highly Cited
2009
Highly Cited
2009
Effects of tonabersat on migraine with aura: a randomised, double-blind, placebo-controlled crossover study
A. Hauge
,
M. S. Asghar
,
H. Schytz
,
K. Christensen
,
J. Olesen
Lancet Neurology
2009
Corpus ID: 36378558
2009
2009
Efficacy and Safety of Tonabersat, a Gap-Junction Modulator, in the Acute Treatment of Migraine: A Double-Blind, Parallel-group, Randomized Study
Cgh Dahlö
,
AW Hauge
,
J. Olesen
Cephalalgia
2009
Corpus ID: 205586437
The ability of tonabersat to relieve the symptoms of migraine attacks with or without aura was evaluated in a randomized, double…
Expand
2001
2001
Diffusion-Weighted MRI Used to Detect in Vivo Modulation of Cortical Spreading Depression: Comparison of Sumatriptan and Tonabersat
D. Bradley
,
M. Smith
,
+7 authors
M. James
Experimental Neurology
2001
Corpus ID: 46501309
Spreading cortical depolarization and depression of electroencephalographic activity (SD) may underlie the aura and spreading…
Expand
2001
2001
Tonabersat (SB‐220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve‐induced neurovascular reflexes
A. A. Parsons
,
S. Bingham
,
P. Raval
,
S. Read
,
M. Thompson
,
N. Upton
British Journal of Pharmacology
2001
Corpus ID: 30086977
The effects of tonabersat (SB‐220453) were evaluated on trigeminal nerve ganglion stimulation‐induced sensory‐autonomic…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE