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tmRNA

Known as: 10Sa RNA, SsrA, Transfer-Messenger RNA 
An RNA encoded by the bacterial ssrA gene. It is involved in the recycling of stalled ribosomes and the targeting of both defective mRNA molecules… 
National Institutes of Health

Related topics

Related topics

2 relations
Clinical Data Interchange Standards Consortium Terminology

Broader (1)

RNA, Bacterial

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection
In most bacteria, Clp protease is a conserved, non-essential serine protease that regulates the response to various stresses… 
Highly Cited
2008
Highly Cited
2008
Integrated microfluidic tmRNA purification and real-time NASBA device for molecular diagnostics.
We demonstrate the first integrated microfluidic tmRNA purification and nucleic acid sequence-based amplification (NASBA) device… 
Highly Cited
2007
Highly Cited
2007
SseL, a Salmonella deubiquitinase required for macrophage killing and virulence
Expression of the Salmonella enterica serovar Typhimurium pathogenicity island 2 (SPI-2) type III secretion system is controlled… 
Highly Cited
2003
Highly Cited
2003
Cleavage of the A site mRNA codon during ribosome pausing provides a mechanism for translational quality control.
Highly Cited
2002
Highly Cited
2002
ClpS, a substrate modulator of the ClpAP machine.
Highly Cited
2001
Highly Cited
2001
Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome.
Highly Cited
2000
Highly Cited
2000
PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone
The proteasome-activating nucleotidase (PAN) from Methanococcus jannaschii is a complex of relative molecular mass 650,000 that… 
Highly Cited
1999
Highly Cited
1999
SmpB, a unique RNA‐binding protein essential for the peptide‐tagging activity of SsrA (tmRNA)
In bacteria, SsrA RNA recognizes ribosomes stalled on defective messages and acts as a tRNA and mRNA to mediate the addition of a… 
Highly Cited
1999
Highly Cited
1999
SsrA‐mediated peptide tagging caused by rare codons and tRNA scarcity
SsrA RNA mediates the addition of a C‐terminal peptide tag (AANDENYALAA) to bacterial proteins translated from mRNAs without in… 
Highly Cited
1995
Highly Cited
1995
C-terminal Extension of Truncated Recombinant Proteins in Escherichia coli with a 10Sa RNA Decapeptide(*)
When murine interleukin-6 is overexpressed in Escherichia coli, a small population of molecules exhibits a novel C-terminal… 
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