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Hypoxic pulmonary vasoconstriction (HPV) is initiated by inhibition of O2-sensitive, voltage-gated (Kv) channels in pulmonary… Expand Previous research from our Laboratory has shown a greater susceptibility of young animals, when compared to adults, to… Expand In this work we submitted adult male Wistar rats to intracerebroventricular (icv) and iv microinjections of the fraction… Expand Cultured neuronal networks, which have the capacity to respond to a wide range of neuroactive compounds, have been suggested to… Expand Octopus cells in the posteroventral cochlear nucleus (PVCN) of mammals are biophysically specialized to detect coincident firing… Expand NEUROTOXINS can help the understanding of mechanisms involved in neurotransmission. We here report that two neurotoxin isoforms… Expand Abstract The concentration of extracellular excitatory amino acids in the striatum of conscious, unrestrained rats was measured… Expand When tityustoxin (TsTX, 1.43 muM; mol. wt. 6995) was applied to the rat phrenic nerve-diaphragm muscle preparation, both the… Expand The increase in the release of acetylcholine (ACh) from cortical slices of rat brain elicited by the depolarizing agents, ouabain… Expand Abstract— Purified tityustoxin (TsTX) from the venom of the scorpion, Tityus serrulatus, when incubated in vitro with slices of… Expand