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tiotropium bromide
Known as:
7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide
, Bromide, Tiotropium
, Tiotropium Bromide [Chemical/Ingredient]
The bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity…
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National Institutes of Health
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Related topics
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16 relations
28 ACTUAT tiotropium 0.0025 MG/ACTUAT Metered Dose Inhaler [Spiriva]
60 ACTUAT tiotropium 0.0025 MG/ACTUAT Metered Dose Inhaler [Spiriva]
In Blood
agonists
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Narrower (4)
BA 679 BR
Spiriva
olodaterol / tiotropium
tiotropium
Broader (3)
Bronchodilator Agents
Cholinergic Antagonists
Parasympatholytics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Emerging therapeutic options for the treatment of patients with symptomatic asthma.
R. McIvor
Annals of Allergy, Asthma & Immunology
2015
Corpus ID: 38403835
2014
2014
The in vitro and in vivo profile of aclidinium bromide in comparison with glycopyrronium bromide.
A. Gavaldà
,
I. Ramos
,
+9 authors
M. Miralpeix
Pulmonary Pharmacology & Therapeutics
2014
Corpus ID: 6872069
Highly Cited
2014
Highly Cited
2014
Effects of tiotropium on hyperinflation and treadmill exercise tolerance in mild to moderate chronic obstructive pulmonary disease.
R. Casaburi
,
F. Maltais
,
+5 authors
D. O’Donnell
Annals of the American Thoracic Society
2014
Corpus ID: 27506880
RATIONALE Bronchodilator therapy represents a potentially valuable therapeutic option to increase exercise tolerance and enhance…
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Review
2010
Review
2010
The cardiovascular risk of tiotropium: is it real?
M. Cazzola
,
L. Calzetta
,
M. Matera
Expert Opinion on Drug Safety
2010
Corpus ID: 43592437
Importance of the field: Anticholinergic agents are of noteworthy value in the treatment of chronic obstructive pulmonary disease…
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Highly Cited
2009
Highly Cited
2009
Outcomes associated with tiotropium use in patients with chronic obstructive pulmonary disease.
Todd A. Lee
,
C. Wilke
,
+4 authors
A. S. Pickard
Archives of Internal Medicine
2009
Corpus ID: 12950174
BACKGROUND To date, there is mixed evidence on the safety and effectiveness of tiotropium. Our objective was to evaluate the…
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2009
2009
Efficacy and Safety of Nebulized Formoterol as Add-on Therapy in COPD Patients Receiving Maintenance Tiotropium Bromide
N. Hanania
,
Ahmad Boota
,
E. Kerwin
,
L. Tomlinson
,
K. Denis-Mize
Drugs
2009
Corpus ID: 3633460
AbstractBackground: Current guidelines for the treatment of chronic obstructive pulmonary disease (COPD) recommend the use of…
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2008
2008
Suppressive activity of tiotropium bromide on matrix metalloproteinase production from lung fibroblasts in vitro
K. Asano
,
Y. Shikama
,
+4 authors
H. Suzaki
International Journal of COPD
2008
Corpus ID: 16824060
Background Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with an accumulation of…
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2007
2007
Tiotropium and simplified detection of dynamic hyperinflation.
A. Gelb
,
C. Taylor
,
+5 authors
N. Zamel
Chest
2007
Corpus ID: 10881443
STUDY OBJECTIVE To detect dynamic hyperinflation (DH) by evaluating reduction in inspiratory capacity (IC) during metronome-paced…
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Review
2007
Review
2007
Use of inhaled anticholinergic agents in obstructive airway disease.
Ruben D. Restrepo
Respiratory care
2007
Corpus ID: 40254710
In the last 2 decades, anticholinergic agents have been generally regarded as the first-choice bronchodilator therapy in the…
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Review
2005
Review
2005
The Role of Tiotropium Bromide, a Long-Acting Anticholinergic Bronchodilator, in the Management of COPD
F. Saberi
,
D. O’Donnell
Treatments in Respiratory Medicine
2005
Corpus ID: 44773810
Bronchodilator therapy forms the mainstay of treatment for symptomatic patients with COPD. Long-acting bronchodilators, which…
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