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tiotropium bromide

Known as: 7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide, Bromide, Tiotropium, Tiotropium Bromide [Chemical/Ingredient] 
The bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
RATIONALE Bronchodilator therapy represents a potentially valuable therapeutic option to increase exercise tolerance and enhance… 
Review
2010
Review
2010
Importance of the field: Anticholinergic agents are of noteworthy value in the treatment of chronic obstructive pulmonary disease… 
Highly Cited
2009
Highly Cited
2009
BACKGROUND To date, there is mixed evidence on the safety and effectiveness of tiotropium. Our objective was to evaluate the… 
2009
2009
AbstractBackground: Current guidelines for the treatment of chronic obstructive pulmonary disease (COPD) recommend the use of… 
2008
2008
Background Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with an accumulation of… 
2007
2007
STUDY OBJECTIVE To detect dynamic hyperinflation (DH) by evaluating reduction in inspiratory capacity (IC) during metronome-paced… 
Review
2007
Review
2007
In the last 2 decades, anticholinergic agents have been generally regarded as the first-choice bronchodilator therapy in the… 
Review
2005
Review
2005
Bronchodilator therapy forms the mainstay of treatment for symptomatic patients with COPD. Long-acting bronchodilators, which…