tiotropium bromide

Known as: 7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide, Bromide, Tiotropium, Tiotropium Bromide [Chemical/Ingredient] 
The bromide salt form of tiotropium, a quaternary ammonium derivative of atropine and a muscarinic receptor antagonist, with bronchodilating activity… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
STUDY OBJECTIVES Neutrophil influx into the airways is an important mechanism in the pathophysiology of the inflammatory process… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
BACKGROUND Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose asthma is poorly controlled by an inhaled… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
2010
2010
BACKGROUND Tiotropium bromide, a long acting muscarinic receptor inhibitor, is a potent agent for patients with bronchial asthma… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Tiotropium bromide is a long acting muscarinic antagonist (LAMA), marketed under the brand name Spiriva, for the treatment of… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
RATIONALE Exacerbations are key drivers of morbidity and mortality in chronic obstructive pulmonary disease (COPD). OBJECTIVES… (More)
  • figure 1
  • table 2
  • table 1
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND The combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) are commonly used… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2008
2008
Although currently available asthma medications are very effective in the majority of cases, there remains a subgroup for which… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Chronic inflammation in asthma and chronic obstructive pulmonary disease drives pathological structural remodelling of the… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
RATIONALE Recent findings have demonstrated that muscarinic M(3) receptor stimulation enhances airway smooth muscle proliferation… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND In chronic obstructive pulmonary disease (COPD), the degree of circadian variation in forced expiratory volume in 1… (More)
  • table 1
  • table 2
  • figure 2
  • figure 1
  • table 3
Is this relevant?